摘要
目的:探讨海口地区妇女人乳头瘤病毒(HPV)感染状况及其危险因素,为防治人乳头瘤病毒感染提供依据。方法:对海口地区3 230名妇女进行横断面调查,采用实时荧光PCR检测人乳头瘤病毒含量,并分析危险因素与人乳头瘤病毒感染的关系。结果:人乳头瘤病毒阳性表达率为30.34%(980/3 230);不同性生活持续年龄段的HPV感染罹患率无统计学差异(P>0.05);单因素分析显示,婚外性行为、吸烟、结婚次数>1、子宫颈糜烂/息肉、阴道滴虫及尿路感染等均是HPV感染的相关因素(OR值分别为1.691、1.571、1.410、1.230、1.260、1.571);多因素分析显示,人乳头瘤病毒感染与婚外性行为、尿路感染等显著相关(OR值分别为1.660、1.541)。结论:海口地区妇女HPV感染率较高,在性生活持续各年龄段均需预防HPV感染,而婚外性行为、尿路感染等是本地区妇女HPV感染的危险因素。
Objective: To explore the status and risk factors of human papillomavirus (HPV) infection among the women in Haik- ou, provide a basis for prevention and treatment of HPV infection. Methods: A cross - sectional survey was conducted among 3 230 women in Haikou, real- time fluorescent PCR was used to detect HPV content, the relationship between risk factors and HPV infection was analyzed. Results: The positive expression rate of HPV was 30. 34% (980/ 3 230) ; there was no statistically significant difference in HPV infectionrate among the women with different duration ages of sexual life (P 〉 0. 05) ; the results of univariate analysis showed that fornication, smok- ing, times of marriage 〉 1, cervical erosion/polyp, Trichomonas vaginalis infection and urinary tract infection were related factors of HPV in- fection ( OR values: 1. 691, 1. 571, 1. 410, 1. 230, 1. 260, 1. 571 ) ; the results of multivariate analysis showed that HPV infection was sig- nificantly correlated with fornication, urinary tract infection ( OR values : 1. 660, 1. 541 ) . Conclusion: HPV infection rate in the women in Haikou is relatively high, the women in all the ages of sexual life need prevention of HPV infection ; fornication and urinary tract infection are risk factors of HPV infection in the women in Haikou.
出处
《中国妇幼保健》
CAS
北大核心
2014年第21期3466-3469,共4页
Maternal and Child Health Care of China
基金
国家自然科学青年基金(81202959)
海南省自然科学基金项目(80463)
关键词
人乳头瘤病毒
妇女
横断面调查
危险因素
Human papillomavirus
Woman
Cross - sectional survey
Risk factor