2型糖尿病患者焦虑和抑郁现状及危险因素的研究

The risk factors for anxiety and depression in patients with type 2 diabetes in Xuzhou

目的 研究T2DM患者焦虑、抑郁现状，并探讨其危险因素。 方法 采用多阶段整群随机抽样方法，采用Logistic回归分析调查473例T2DM（T2DM组）患者及473名健康对照者（NC组）焦虑、抑郁的危险因素。 结果 T2DM组焦虑和抑郁患病率分别为38.9%和31.9%，均高于NC组（16.9%和18.2%）。回归方程显示，病程（5.1～10.0年，OR=2.136）、合并抑郁（OR=3.044）和女性（OR=1.687）是T2DM患者焦虑的危险因素，家庭月收入高（≥5001元，OR=0.191）是其保护因素;年龄（61～70岁，OR=1.896）、文化水平低（小学及以下，OR=2.717）、居住方式（仅与子女居住，OR=2.532）、有并发症（OR=1.775）和焦虑（OR=3.66）是T2DM患者抑郁的危险因素。 结论 T2DM患者焦虑和抑郁患病率均高于一般人群。T2DM患者合并焦虑情绪可能与病程、家庭月收入及性别有关。T2DM患者合并抑郁可能与高龄、低文化水平、与子女居住和合并并发症有关。

Objective To investigate the prevalence of anxiety and depression in the patients with type 2 diabetes and to analyze the risk factors of anxiety and depression. Methods 473 cases with type 2 diabetes （T2DM group） and 473 control cases （NC group）were selected by multi-stage cluster random sampling method, and the risk factors of anxiety and depression in the subjects were analyzed using multivariate factors non-conditional logistic regression model. Results The prevalence of anxiety and depression in T2DM group were 38.9% and 31.9%, which were higher than those in NC group （16.9% and 18.2%, respectively）. Logistic regression equation showed that course of the disease（5.1～10 years, OR = 2.136 ）, depression （OR=3.044）, female （OR = 1.687 ） were risk Factors of anxiety in patients with T2DM, while family income （≥5001yuan, OR =0.191） was the protective factor of anxiety in patients with type 2 diabetes. Logistic regression equation showed that age （61～70 years, OR = 1.896）, education level （Primary and lower, OR =2.717）, dwelling form （living with children, OR=2.532） , complications （OR = 1.775） and anxiety （OR= 3.66） were risk factors for depression in patients with type 2 diabetes. Conclusions Compared with healthy people, the prevalences of anxiety and depression in patients with type 2 diabetes were significantly increased. Course （5.1 ~ 10 years）, low family income and women with diabetes were prone to anxiety. Older age, low education, living with children and complications of patients were prone to depression.