佛山地区流行性出血热的临床特点及预后影响因素的研究

Clinical features of epidemic hemorrhagic fever and influencing factors of prognosis in Foshan area

目的 为了解佛山地区近十年流行性出血热的临床特点及预后影响的危险因素,特开展此研究.方法 分析390例流行性出血热病人的临床资料的特点,并对疾病严重程度的相关因素作相关分析.结果 所有病例均有发热症状,以腰痛、乏力、腹泻为主;仅有71.8％患者经特异性IgM抗体阳性检测证实;具有典型临床五期经过者占43.6％;实验结果显示,多数患者存在肝、肾、肺、心等不同程度损伤;血液净化、严重器官损害、肾功能、五期经过与疾病严重程度关系较为密切.结论 为避免漏诊,应加强血小板、尿蛋白等血清学检查.

Objective To understand the clinical features of epidemic hemorrhagic fever and prognosis influencing factors in Foshan area in the past 10 years.Methods 390 cases of patients with clinical features of HERS data,and related factors of disease severity correlation analysis were studied.Results All patients had fever symptoms,back pain,fatigue and diarrhea.Only 71.8％ of patients were detected specific IgM antibodies confirmed as positive.Those with five phases of the typical clinical accounted for 43.6％.Experimental results showed that the majority of patients had liver,kidney,lung,heart and other varying degrees of damage.Blood purification,severe organ damage,kidney function,and five phases process had a closer relationship with the severity of the disease.Conclusion To avoid missed diagnosis,platelet serology and urine protein inspection should be enhanced.