痰热清和维生素K_1辅助治疗小儿支气管肺炎的疗效观察

Observation on the effect of tanreqing and vitamin K1in the adjuvant treatment of children bronchial pneumonia

目的观察痰热清和维生素K1辅助治疗支气管肺炎的临床疗效及安全性。方法将小儿支气管肺炎患儿112例随机分为观察组和对照组,各56例,两组均给予抗菌、止咳、祛痰、退热及维持水电解质平衡和酸碱平衡常规治疗,并视病情给予吸氧、吸痰、镇静等基础治疗。观察组在常规治疗的基础上给予痰热清和维生素K1静滴,对照组给予炎琥宁静滴,比较两组的临床疗效及药物不良反应的发生率。结果观察组的总有效率为92.9%,高于对照组的78.6%,差异具有统计学意义(P<0.05)。治疗后在发热天数、咳嗽症状、肺部啰音消失(退)等方面观察组明显优于对照组,差异具有统计学意义(P<0.05)。两组均未发生明显的药物不良反应。结论痰热清和维生素K1辅助治疗小儿支气管肺炎有较好的疗效,且无不良反应,值得临床推广应用。

Objective To observe the clinical efficacy and safety of tanreqing injection and vitamin K 1 in the adjuvant treatment of children bronchial pneumonia .Methods One hundred and twelve children with bronchial pneumonia were randomly divided into observation group and control group .The two groups were given antibiotic ,antitussive cough medicine , expectorant,antifebrile and the maintenance of water and electrolyte balance and acid-base balance .And according to changes of disease given oxygen , suction sputum , sedative and other foundation treatment . On the basis of above routine treatment the observation group was gaved intravenous drip of tanreqing and vitamin K 1 and the control group was treated with intravenous drip of Yanhuning ,the clinical efficacy and incidence of adverse drug reactions between the two groups were compared .Results The total effective rate of observation group was higher than that of the control group （ 92.9% vs 78.6%） , the difference was statistically significant （ P〈0.05 ） .After treatment,in the days of fever , disappearance of cough ,and pulmonary rales , the observation group was better than the control group ,the difference was statistically significant （ P〈0.05 ） .The two groups were not found significant ad-verse drug reactions .Conclusion Tanreqing and vitamin K 1 in the adjuvant treatment in children bronchial pneumonia have better therapeutic effect ,and no adverse reaction was found .It is worthy of clinical application .