外周血白细胞与急性心肌梗死并发应激性溃疡关系研究

Stress Ulceration and White Blood Cell Count in Patients with Acute Myocardial Infarction

目的:探讨外周血白细胞计数(WBC)与急性心肌梗死(AMI)患者并发应激性溃疡(SU)的相关性。方法:选择急性心肌梗死患者218例,白细胞计数采集入院24h内的外周静脉血,根据白细胞计数,将以上患者随机分为白细胞增高组(WBC>10×109L-1),即实验组和白细胞降低组(WBC<10×109L-1)即对照组。经统一方法治疗7d后比较两组的应激性溃疡发生率,并探讨其相关性。结果:WBC增高组并发应激性溃疡的例数高于对照组,有显著差异性(P<0.05)。WBC水平与应激性溃疡的发生呈正相关(P<0.05)。结论:白细胞增高的急性心肌梗死患者建议早期预防应激性溃疡。

Objective：To study the relation between blood cell count and stress ulceration in patients with acute myocardial infarction .Method：218 patients with acute myocardial infarction were recruited , and blood samples were obtained in the first 24 hours after patients arrived hospital for blood count .They were di-vided into two groups according white blood cell count （WBC）：WBC increased group （WBC〉10×10^9L^-1） and control group （ WBC〈10 ×10^9 L^-1 ） .Incident of stress ulceration and the relation between stress ulceration and WBC were analyzed .Result：Incident of stress ulceration was significantly higher in the WBC increased group than that in the control group （P〈0.05）.WBC count has a positive correlation with stress ulceration rate （ P〈0.05） .Conclusion：Something should be done to prevent stress ulceration in acute myocardial in-farction patients with increased WBC .