玉屏风颗粒联合孟鲁司特和布地奈德治疗儿童感染后咳嗽的疗效观察

Curative Effect Observation of Yupingfeng Granule Combined with Montelukast and Budesonide in Treating Children Cough After Infection

目的对玉屏风颗粒联合孟鲁司特和布地奈德治疗儿童感染后咳嗽的临床疗效进行分析和探讨。方法将我院2011年8月至2013年8月收治的120例感染后咳嗽患儿按随机数字表法随机分为治疗组和对照组,每组60例。治疗组患儿给予玉屏风颗粒联合孟鲁司特和布地奈德治疗,对照组患儿给予孟鲁司特+布地奈德治疗。分析和比较两组患儿的治疗效果。结果治疗组显效38例;有效15例,无效7例;总有效率为88.33%。对照组患儿显效22例,有效18例,无效20例;总有效率为66.67%。两组间的比较具有统计学意义(P<0.05)。治疗组患儿咳嗽缓解时间为(5.6±1.5)d,咳嗽消失时间为(7.1±1.2)d,半年内因感染咳嗽就诊的次数为(1.4±0.9)次。对照组患儿咳嗽缓解时间为(7.0±2.5)d,咳嗽消失时间为(8.6±1.8)d,半年内因感染咳嗽就诊的次数为(2.6±1.7)次。两组间的比较差异显著(P<0.05)。结论应用玉屏风颗粒联合孟鲁司特及布地奈德治疗儿童感染后咳嗽效果显著,安全可靠,可有效降低患儿气道的高反应性,在改善患儿临床症状的同时大大提高了患儿的机体免疫力,值得临床推广使用。

Objective To analyze and discuss the clinical effect ofYuping Feng particles combined with montelukast and budesonide in treating children cough aider infection. Methods 120 cases of infection in our hospital fxom 2011 August to 2013 August were randomly divided into treatment group and control group, with 60 cases in each group. The treatment group were given the Yupingfeng granule combined with montelukast and budesonide treatment. The control group were treated with montelukast and budesonide. The primary outcome was an analysis and comparison of two groups of treatment of children. Results The treatment group were 38 excellent cases; 15 effective cases, 7 ineffective cases, and the total effective rate was 88.33%. In the control group were 22 excellent cases, 18 effective cases, 20 ineffective cases, and the total effective rate was 66.67%. There were statistical significance between the two groups （P 〈0.05）. In the treatment group, the cough relief time was （5.6 ＋ 1.5） d, the cough disappeared time was （7.1 ＋ 1.2） d, and the number of visits were （1.4 ^- 0.9）. In the control group, the cough relief time was （7 -＋ 2.5） d, the cough disappeared time was （8.6 ＋ 1.8） d, and the number of visits were （2.6 ＋ 1.7）. There was significant difference between the two groups （_P 〈0.05）. Conclusions Application of Yupingfeng granule combined with montelukast and budesonide as the treatment for children with cough after infection is safe and reliable, which can effectively reduce the high reaction of airway in children, improve the clinical symptoms in children, greatly improve the body immunity of children, and deserve clinical application and promotion.