聚乙二醇联合开塞露提高便秘病人肠镜检查肠道清洁度的效果研究

The efficacy of polyethylene glycol in combination with glycerine enema in bowel preparation of patients with constipation

目的探讨聚乙二醇电解质联合开塞露在提高便秘患者肠镜检查肠道清洁度的作用。方法将120例拟行结肠镜检查的慢性便秘患者随机分成试验组和对照组,对照组患者在结肠镜检查前予口服聚乙二醇电解质2L清洁肠道,试验组在此基础上检查前一天晚上睡前予果导2片口服,并在服用聚乙二醇电解质到一半时予开塞露60ml塞肛。比较2组首次大便时间、大便次数、大便清澈时间及肠道清洁度。结果试验组无论在首次大便时间、大便清澈时间都短于对照组(P<0.01),排便次数高于对照组(P<0.01),镜下肠道清洁度试验组为91.67%明显高于对照组的65.00%,差异有统计学意义(P<0.05)。结论口服聚乙二醇电解质联合开塞露塞肛的方法,可以缩短慢性便秘患者的肠道清洁时间,提高肠道清洁度,是一种值得临床推广使用的肠道准备方法。

Objective To compare the clearing effect between the combination use of glycerine enema plus polyethylene glycol（PEG）and the use of PEG only for the colonoscopy preparation of patients with constipation.Method Patients with the number of 120 who would have colonoscopy were randomly divided into experimental group and control group,and each group included 60 patients.PEG of 2 L was given in control group.Whereas in the experimental group,glycerine enema of 60 ml was used when patients took half the amount of PEG,and 2 tab-lets of phenolphthalein were also given to patients before sleep the day before colonoscopy.To compare the time of the first defecation,the time of completion of bowel cleaning,the frequency of defecation and the cleaning quality of the bowel.Result The time of the first defecation and the time of the completion of bowel cleaning of the experimental group were shorter（P 〈0.01）.The frequency of defecation of the experimen-tal group was higher （P 〈0.01）.The cleaning quality of the bowel in the experimental group was also higher （P 〈0.05）.Conclusion the combination use of glycerine enema plus polyethylene glycol（PEG）for colonoscopy preparation of patients with constipation tends to shorten the time of completion of bowel cleaning and improve the cleaning quality of the bowel.