腹型癫痫56例脑电图及临床治疗分析

Abdominal epilepsy in 56 cases:EEG appearance and clinical analysis

目的对腹型癫痫的脑电图及临床治疗进行分析。方法选择1993年2月—2013年6月治疗的腹型癫痫患儿56例,随机分为对照组与实验组各28例。所有患儿在治疗前后均进行脑电图检查。对照组给予鲁米那、丙戊酸钠、苯巴比妥等抗癫痫药物进行治疗,同时配合脑康复训练及神经细胞营养剂、脑复新等辅助治疗。实验组在常规治疗的基础上给予补肾健脾治疗。治疗期间需要密切观察药物的不良反应,若出现不良反应需改变治疗方案,严重者需及时采取救治措施。需定期进行血常规及肝肾功能常规检查。两组均连续治疗24周,并对所有患儿随访6个月～3年。计量资料采用t检验,计数资料采用χ^2检验,P〈0.05为差异有统计学意义。结果脑电图异常率100.00%,其中轻度异常18例,中度异常27例,重度异常11例。总有效率对照组64.29%,实验组89.28%,比较差异有统计学意义（P〈0.05）。结论脑电图检查对临床腹型癫痫的诊断、治疗效果及预后评价有着十分重要的临床意义,治疗时采用补肾健脾法可以明显提高治疗效果,值得推广应用。

Objective To analyze the EEG appearance and clinical treatment of abdominal epilepsy.Methods 56 children with abdominal epilepsy treated from Feb.1993 to Jun.2013 were randomly divided into control group and experimental group,28 cases for each group.All children received EEG examination before and after treatment.Control group received luminal,sodium evaporate,phenobarbital and other anti- epileptic drugs,as well as brain rehabilitation exercises,nutrients for nerve cells,pyritinol and other adjuvant treatment.Experimental group received drugs for supplementing the kidney and fortifying the spleen in addition to conventional therapy.All cases should to be closely observed for adverse reactions during treatment,if present,treatment regimens should be changed,and treatment measures should be taken timely in severe cases.Blood routine and liver and kidney function examination should be performed regularly.Both groups were treated for 24 consecutive weeks and were followed up for 6 months to 3 years.T- test was used for measurement data,count data were processed by χ^2 test,the result of P〈0.05 was considered statistically significant.Results The rate of EEG abnormality was 100.00%,of which 18 cases were of mild abnormality,27 cases of moderate abnormality,11 cases of severe abnormality.The total effective rate was 64.29% in control group and 89.28% in experimental group.The difference was statistically significant（P〈0.05）.Conclusion EEG is of great clinical significance to the diagnosis,treatment and prognosis of abdominal epilepsy.The method of supplementing the kidney and fortifying the spleen can significantly improve the therapeutic effects,which is worthy of being widely applied.