当归饮子治疗血液透析皮肤瘙痒症随机平行对照研究

Pruritus Randomized Parallel Group Study Angelica Yinzi Treatment

[目的]观察当归饮子治疗血液透析皮肤瘙痒症疗效。[方法]使用随机平行对照方法,将123例住院患者按抽签法分为两组。对照组62例西替利嗪片,10mg/次,1次/d,晚间口服;酮替芬,1mg/次,1次/d,晚间口服。治疗组61例当归饮子（玄参、麦冬、沙参各20g,白茅根30g,刺蒺藜15∽30g,川芎10g,丹参、当归各20g,鸡血藤30g,生地、丹皮各15g,熟地、夜交藤、茯苓、酸枣仁各20g,陈皮10g;久病需增加刺蒺藜剂量）,1剂/d,冷水煎150mL,早晚口服。连续治疗30d为1疗程。观测临床症状、不良反应。治疗1疗程,判定疗效。[结果]治疗组显效43例,有效7例,无效11例,总有效率81.96%。对照组显效19例,有效8例,无效35例,总有效率43.55%。治疗组疗效优于对照组（P〈0.01）。[结论]当归饮子治疗血液透析皮肤瘙痒症效果显著,值得推广。

[Objective] To observe Angelica Yinzi side effect of the treatment of pruritus. [Methods ] Random parallel control method,123 cases of hospitalized patients were divided into two groups by drawing lots. A control group of 62 patients cetirizine tablets,10mg / times,1 times / d,orally evening; ketotifen,1mg / times,1 times / d,orally evening. Treatment group of 61 patients Angelica Yinzi party（Xuanshen,Maidong,Shashen 20g,Baimaogen 30g,Cijili 15 ~ 30g,Chuanxiong 10g,Danshen,Dangui 20g,Jixueteng 30g,Shengdi,Danpi 15g,Shudi,Yejiaoteng,Fuling,Suanzaoren each 20g,Chenpi 10g; chronic illness need to increase the dose of Cijili）,1 does/ d,cold decoction 150 mL,sooner or later,oral. 30 d is a continuous course of treatment. Observing clinical symptoms of adverse reactions. A course of treatment to determine efficacy. [Results] 43 cases markedly effective in 7 cases,11 cases,the total efficiency of 81.96%. The control group 19 cases,8 cases,ineffective in 35 cases,the total efficiency 43.55%. Treatment group than the control group（P 0.01）. [Conclusion ] Angelica Yinzi Treatment of pruritus effect is significant,it is worth promoting.