辨证分型联合西药治疗冠心病随机平行对照研究

Medicine Plus Western Treatment of Coronary Heart Disease Randomized Parallel Group Study

[目的]观察辨证分型联合西药治疗冠心病疗效。[方法]使用随机平行对照方法,将72例门诊及住院患者按抽签法分为两组。对照组36例,分期使用硝酸甘油、消心痛及硝酸酯、钙通道阻滞剂等。治疗组36例辨证分型,寒凝心脉,莲子大枣汤(莲子12g,大枣9枚,黄茂15g,桂枝、当归各6g,细辛3g,赤芍6g,甘草12g);心气阻滞,川芎香附汤(川芎、香附各10g,陈皮6g,白芍、麸炒枳壳各10g,柴胡6g,甘草炙5g);气虚血瘀,丹参益母草汤(丹参15g,益母草30g,川芎10g,三七3g,人参6g,当归9g,红参6g,红花12g,甘草6g);痰浊闭阻,瓜蒌半夏汤(瓜蒌实24g,薤白9g,半夏12g,白酒适量);心气不足,茯苓人参汤(茯苓15g,人参10g,酸枣仁炒15g,远志炙、半夏各10g,黄芪炙、当归、川芎各15g,柏子仁、五味子各10g,肉桂5g,甘草炙12g);1剂/d,水煎200mL,早晚口服;西药治疗同对照组。连续治疗14d为1疗程。观测临床症状、症候积分、心绞痛发作、不良反应。治疗1疗程,判定疗效。[结果]治疗组显效21例,有效9例,无效6例,总有效率83.33%。对照组显效17例,有效10例,无效9例,总有效率75.00%。治疗组疗效优于对照组(P<0.05)。[结论]辨证分型联合西药治疗冠心病效果显著,值得推广。

[ Objective ] To observe Medicine plus Western medicine treatment of coronary heart disease treatment. [ Methods ] Random parallel control method, 72 cases of outpatient and inpatient divided into two groups by drawing lots. According to the control group of 36 patients with acute exacerbation of angina, myocardial ischemia different remission were given nitroglycerin, isosorbide dinitrate and nitrates, calcium channel blockers and other treatment. Treated 36 cases of syndrome differentiation. （1） Hanning Xinmaitong, lotus Dazao （Lianzi 12g, 9 Dazao, Huangmao 15g, Guizhi, Dangui 6g, Xixin 3g, Chishao 6g, Gancao 12g ） ; （2） heart gas block, Chuan Xiong Xiang Fu Tom （ Chuanxiong, Xiangfu each 10g, Chenpi 6g, Baishao, fried Jike 10g, Chaihu 6g, Gancao fried 5g ） ; （3） blood stasis, motherwort soup Salvia （ Danshen 15g, Ymucao30g, Chuanxiong 10g, Sanqi 3g, Renshen 6g, Dangui 9g, Hongshen 6g, Honghua 12g, Gancao 6g ） ; （4） phlegm closed block, Gualou Decoction （ Gualoushi 24g, Xiebai 9g, Banxia 12g, amountof Baijiu ） ; （5） heart qi deficiency, Poria ginseng （ Fnling 15g, Renshen 10g, Suanzaoren fried 15g, Yuanzhi fried, Banxia each 10g, Huangqi fried, Dangui, Chuanxiong each 15g, Boziren, Wuweizi each 10g, Rougui 5g, Gancao fried 12g） ; The above herbs are 1 / d, decoction 200mL, sooner or later, oral; western medicine with the control group. 14d is a continuous course of treatment. Observing clinical symptoms of adverse reactions. A course of treatment to determine efficacy. [ Results ] Treatment group 21 cases, 9 cases, 6 cases, the total efficiency of 83.33%. The control group 17 cases, 10 cases, 9 cases, the total efficiency of 75.00%. Treatment group than the control group （ P 〈0.05 ） . [ Conclusion ] Western medicine treatment of coronary artery disease syndrome differentiation combined effect is significant, it is worth promoting.