干预后呼吸内科门诊抗菌药使用合理性分析

Analysis of Rational Usage of Antimicrobial Drugs after the Intervention of Respiratory Medicine Outpatient

目的:了解临床药师干预后呼吸内科门诊抗菌药的使用情况方法:采用回顾性调查方法,抽取干预当月,干预后第3、5月的我院呼吸内科门诊所有抗菌药处方,对使用抗菌药的比例、品种、药物利用指数(DUI)、联用情况及合理性进行分析。结果:干预当月点评抗菌药处方210张,干预后第3、5月分别点评263、437张。通过干预呼吸内科抗菌药使用率有20.53%下降到干预后第5月下降到17.53%(P>0.05);抗菌药的联用比例由干预当月的12.38%下降至干预第5月的5.95%(P<0.01);抗菌药不合理处方比例由3.35%下降至干预后第5月的0.46%(P<0.01)。结论:通过持续的干预后抗菌药使用更加符合安全有效的原则,抗菌药各项指标趋于更加合理。

Objective：To investigate the situation of antimicrobial usage after clinical pharmacist intervention in respiratory medicine clinic. Methods： All respiratory medicine outpatient antibiotic prescriptions after the intervention of the month, its third month and fifth month were extracted by using the retrospective survey method. The proportion, varie- ty, DUI, situation of combined usage and reasonableness of using antimicrobial drugs were analyzed. Results：210 antimi- crobial prescriptions in the month, 263,437 in the third and fifth month after intervention were reviewed. The respiratory medicine antimicrobial usage proportion dropped from 20.53% for the first month intervention to 17.53% for five monthes （P 〉 0.05 ）. The combined usage of antimicrobial drugs dropped from 12.38% of the first month intervention to 5.95% of the fifth month. The irrational prescription of antimicrobial drugs decreased from 3.35% in the first month of intervention to 0.46% in the fifth month of intervention（P 〈0.0I ）. Conclusion： The antimicrobial drugs were more in line with the principles of safety and effectiveness and many norms of antimicrobial drugs tended to be more reasonable through sustained in- tervention of antimicrobial drug usage.