肾交感射频消融术在慢性肾脏病患者高血压治疗的应用研究

Catheter-based renal sympathetic denervation for resistant hypertension in chronic renal failure:recent progress in clinical research

交感神经过度兴奋与慢性肾脏疾病(chronic kidney disease,CKD)患者高血压的发生、发展密切相关。而抗交感药物难以达到降压治疗目标。近年来,肾交感射频消融术(catheter-based renal sympathetic denervation,RSD)迅猛发展,成为了CKD患者治疗高血压新的尝试。本文对此项技术在CKD患者高血压治疗的应用进行探讨。

The occurrence and development of chronic kidney disease（CKD）hypertension is closely related with sympathetic over activity. The anti-hypertensive drugs and anti-sympathetic antihypertensive treatment program are difficult to achieve the target of anti-hypertension. In recent years,catheter-based renal sympathetic denervation technique is developing rapidly,which becomes a novel method to treat resistant hypertension of CKD patients. This paper aims to review the recent progress in this technique.