臭氧化反应在有机合成上的应用 外消旋、左旋、右旋反式-2,2-二甲基-3-异丁烯基环丙烷羧酸及其酯的臭氧化反应研究

Study on the Application of Ozonation in Organic Syntheses

外消旋、左旋和右旋反式-2,2-二甲基-3-异丁烯基环丙烷羧酸(菊酸)和它们的酯,经臭氧化反应很方便地以较高的收率制得了外消旋,左旋及右旋反式-2,2-二甲基-3-醛基环丙烷羧酸(蒈醛酸)和它们的酯。本文叙述了臭氧化反应可能的过程及其机理,研究了反应的温度和溶剂等条件对产物收率的影响。

dl. 1. d-trans-2, 2-dimethyl-3-isobutenyl cyelopropan ecarboxylic acid (ehrysanthemie acid)and their ester were ozonized dy O_3/O_2 mixed gases in some solvent, such as methanol and acetie acid, to give dI. 1. d-trans-2, 2-dimethyl-3-formyleycl propanecarboxylie acid (caronie acid)and its ester with a good yeild.