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强直性脊柱炎生物样本库的建立及意义 被引量:1

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摘要 AS是一种常见的慢性结缔组织炎症性疾病,由于其好发于中青年男性,具有较高的致残、致畸率,现已成为人口与健康领域的研究重点.随着人们对该疾病的日益关注和科研力量的投入,近十几年来在其早期诊断和生物制剂治疗方面已取得一些重要进展,但对于AS一些关键性问题诸如发病机制等方面仍不完全清楚[1],特别是对于在分子水平上控制骨过度形成的机制以及从炎症到强直的病理进程知之甚少[1-2].造成上述困境的原因除AS发病机制本身的复杂性外,另一个主要原因是在科研工作中很难获得AS发病部位的组织标本[3].
出处 《中华风湿病学杂志》 CAS CSCD 北大核心 2014年第7期498-500,共3页 Chinese Journal of Rheumatology
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二级参考文献58

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