益智茎叶中黄酮类化学成分研究

Chemical Constituents of Flavones Part from the Stems and Leaves of Alpinia oxyphylla Miq.

对益智茎叶中黄酮类化学成分进行研究,采用多种色谱方法进行分离纯化,运用多种谱学方法并结合理化性质对分离得到的化合物进行结构鉴定。结果从益智茎叶95%乙醇提取物中共分离得到11个黄酮类化合物,其中包括8个黄酮类化合物,分别鉴定为:良姜素(izalpinin)(1)、杨芽黄素(tectochrysin)(2)、白杨素(chrysin)(3)、芹菜素(apigenin)(4)、刺槐素(acacetin)(5)、5-羟基-4',7-二甲氧黄酮(5-hydroxy-4',7-dimethoxyflavone)(6)、山奈酚-4'-O-甲醚(kaempferol-4'-O-methylether)(7)、5,7,4'-三甲氧基黄酮(5,7,4'-trimethoxyflavone)(8)和3个二氢黄酮类化合物,分别鉴定为:乔松素(pinocembrin)(9)、球松素(pinostrobin)(10)和二氢山萘酚(dihydrokaempferol)(11)。所有化合物均为首次从该植物茎叶中分离得到,其中化合物6、8和10为首次从该属植物中分离得到。

To study the chemical constituents of flavones from the stems and leaves ofAlpinia oxyphyUa Miq.. The chem- ical constituents were isolated by using various column chromatographies and their structures were dueidated on basis of physicochemical constants and spectral data analysis. Consequently,eight flavones and three flavanones were obtained from the 95% ethanol extracts of the stems and the leaves ofAlpinia oxyphylla Miq.. Their structures were determined to be izalpinin （ 1 ）, tectochrysin （ 2 ）, chrysin （ 3 ）, apigenin （ 4 ）, aeacetin （ 5 ）, 5-hydroxy-4＇, 7-dimethoxyflavone （ 6 ）, kaempferol-4＇-O-methylether （ 7 ）, 5,7,4＇-trimethoxyflavone （ 8 ）, pinocembrin （ 9 ）, pinostrobin （ 10 ）, and dihydro- kaempferel（ 11 ）. All those compounds were obtained from the parts of stems and leaves of A. oxyphylla Miq. for the first time, and compounds 6,8, and 10 were obtained from this genus for the first time.