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脊髓血管母细胞瘤的MRI特点 被引量:4

MRI characteristics of spinal cord hemangioblastoma
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摘要 目的分析探讨脊髓血管母细胞瘤的MRI表现特征。方法回顾性分析经手术病理证实的7例脊髓血管母细胞瘤的临床及MRI表现。全部患者均行MRI平扫及增强扫描。结果单发6例,多发1例,共有脊髓血管母细胞瘤病灶8个,所有病灶均位于髓内。其中,延髓1个,颈段4个,胸段2个,腰段1个。肿瘤多呈点状、结节状、香肠状或不规则形状,肿瘤在MRI T1WI呈等或稍低信号,T2WI呈稍高信号,增强扫描上下径<20 mm的病灶呈明显、均匀强化,上下径>20 mm的病灶呈明显不均匀强化,其内可见多发流空的血管影;7例患者均伴有不同程度脊髓空洞或水肿。结论脊髓血管母细胞在MRI中具有特征性的影像表现,MRI对诊断脊髓血管母细胞瘤具有重要价值。 Objective To elucidate the MRI characteristics of spinal cord hemangioblastomas. Methods The clinical data and MRI findings in seven patients with pathologically confirmed spinal cord hemangioblastimas were reviewed retrospectively. All of the patients underwent MRI scan. Results The hemangioblastimas showed single lesion in six patients and showed muhiple lesions in one case by MRI. A total of eight intraspinal hemangioblastimas were located in intramedullary, including single lesion at medulla oblongata, four lesions at the cervical spinal cord, two lesions at the thoracic spinal cord and one lesion at the lumbar spinal cord. Tumors showed point-like or nodular appearance, some of them sausage-like or irregular shape. The tumors were isointensity or slight hypointensity on T1WI and hyperintensity on T2WI. Small(more than 20 mm) tumors showed obviously homogeneous enhancement after contrast injection, however, large (less than 20 mm) tumors showed obviously heterogeneous enhancement. Seven of those 8 tumors were accompanied by vascular flow voids or peritumoral edema. Conclusion The MRI findings of hemangioblastomas in the spinal cord are characteristic. MRI is valuable for establishing the diagnosis preoperately.
出处 《岭南现代临床外科》 2014年第4期441-445,共5页 Lingnan Modern Clinics in Surgery
基金 广东省自然科学基金项目(编号:S20120100084407)
关键词 脊髓肿瘤 血管母细胞瘤 核磁共振成像 Spinal cord tumors Hemangioblastomas Magnetic resonance imaging
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参考文献12

  • 1Park CH, Lee CH, Hyun SJ, et al. Surgical outcome of spinal cord hemangioblastomas [J]. J Korean Neurosurg Soc, 2012, 52(3) : 221-227.
  • 2Mandigo CE, Ogden AT, Angevine PD, et al. Operative management of spinal hemangioblastoma [ J ]. Neurosurgery, 2009, 65(6) : 1166-1177.
  • 3马小龙,魏伟,汪建华,陆建平,王莉,刘崎,蒋慧.von Hippel—Lindau病的影像表现[J].中华放射学杂志,2013,47(4):344-348. 被引量:10
  • 4Mechtler LL, Nandigam K. Spinal cord tumors: new views and future directions [J]. Neurol Clin, 2013, 31(1): 241- 268.
  • 5Baker KB, Moran CJ, Wippold FN, et al. MR imaging of spinal hemangioblastoma [J]. AJR Am J Roentgenol, 2000, 174(2) : 377-382.
  • 6Wu TC, Guo WY, Lirng JF, et al. Spinal cord hemangioblastoma with extensive syringomyelia[J]. J Chin Med Assoc, 2005, 68(1): 40-44.
  • 7Chu BC, Terae S, Hida K, et al. MR findings in spinal hemangioblastoma:correlation with symptoms and with angiog- raphic and surgical findings [J]. AJNR Am J Neuroradiol, 2001, 22(1): 206-217.
  • 8Imagama S, Ito Z, Wakao N, et al. Differentiation of localiz- ation of spinal hemangioblastomas based on imaging and pathological findings[J]. Eur Spine J, 2011, 20(8): 1377- 1384.
  • 9Lonser RR, Weil ILl, Wanebo JE, et al. Surgical management of spinal cord hemangioblastomas in patients with yon Hippel- Lindau disease [J]. J Neurosurg, 2003, 98(1) : 106-116.
  • 10Aguilera DG, Mazewski C, Sehniederjan MJ, et al. Neurofibromatosis-2 and spinal cord ependymomas: Report of two cases and review of the literature [ J ]. Childs Nerv Syst, 2011, 27(5): 757-764.

二级参考文献7

  • 1Maher ER, Neumann HP, Richard S. yon Hippel-Lindau disease : a clinical and scientific review. Eur J Hum Genet, 2011, 19: 617-623.
  • 2Leung RS, Biswas SV, Duncan M, et al. hnaging features of yon Hippel-Lindau disease. Radiographics ,2008,28:65-79.
  • 3Marcos HB, Libutti SK, Alexander HR, et al. Neuroendocrine tumors of the pancreas in yon Hippel-Lindau disease: spectrum of appearances at CT and MR imaging with histopathologic comparison. Radiology, 2002,225 : 751-758.
  • 4Choi JY, Kim M J, Lee JY, et al. Typical and atypical manifestations of serous cystadenoma of the pancreas: imaging findings with pathologic correlation. A JR Am J Roentgenol, 2009, 193 : 136-142.
  • 5Neumann HP, Hoegerle S, Manz T, et al. How many pathways In pheochromocytoma? . Semin Neohrol.2002.22:89-99.
  • 6Choyke PL, Glenn GM, Walther MM, et al. von Hippel-Lindau disease : genetic, clinical, and imaging features. Radiology, 1995, 194:629-642.
  • 7孙灿辉,冯仕庭,彭振鹏,范淼,郭欢仪,李子平,孟悛非.von Hippel—Lindau病胰腺和肾受累的影像表现[J].中华放射学杂志,2009,43(4):378-381. 被引量:7

共引文献9

同被引文献26

  • 1李青,印弘,宋建华.中枢神经系统肿瘤病理学[M].北京:人民卫生出版社,2011:10-14.
  • 2李瑞春,惠旭辉,刘翼,陈海锋,游潮.脊髓髓内血管母细胞瘤的MRI特征[J].临床放射学杂志,2007,26(12):1189-1191. 被引量:19
  • 3Park CH, Lee CH, Hyun SJ, et al. Surgical outcome of spinal cord hemangioblastomas[J]. J Korean Neurosurg Soc, 2012, 52 (3) 221-227.
  • 4Do-Dai DD, Brooks MK,Goldkamp A, et al. Magnetic resonance imaging of intramedullary spinal cord lesions: a pictorial review [J]. Curr Probl Diagn Radiol, 2010,39(4) : 160-185.
  • 5Goy AM, Pinto RS, Raghavendra BN, et al. Intramedullary spinal cord tumors: MR imaging, with emphasis on associated cysts[J]. Radiology, 1986,161 (2) : 381-386.
  • 6Arima H, Hasegawa T, Togawa D, et al. Feasibility of a novel diagnostic chart of intramedullary spinal cord tumors in magnetic resonance imaging[J]. Spinal Cord, 2014,52 (10) : 769-773.
  • 7Lonser RR. Surgical management of sporadic spinal cord heman- gioblastomas[J]. World Neurosurg,2014,82(5) :632-633.
  • 8Wanebo JE, Lonser RR, Glenn GM, et al. The natural history of hemangioblastomas of the central nervous system in patients with yon Hippel-Lindau disease[J]. J Neurosurg,2003,98(1):82-94.
  • 9Zhang Q,Li DL,Kang P,et al. Clinical presentation and mutation analysis of VHL disease in a large Chinese family[J] J Neuroon- col, 2015,125 (2) : 369-375.
  • 10Pruksakorn P, Siwanuwatn R, Snabboon T. Spinal hemangioblas- toma['J]. Am J Med Sci,2011,342(3) :240.

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