摘要
[目的]观察辨证治疗自身免疫性肝炎疗效。[方法]使用随机平行对照方法,将60例住院及门诊患者按就诊顺序编号简单随机分为两组。对照组30例甘草酸二铵胶囊,150mg/次,3次/d,口服;胆红素升高加茵栀黄颗粒,6g/次,3次/d,口服。治疗组30例①湿热蕴结,清利湿热方(薏苡仁、茵陈各30g,山药15g,黄荟、防风、五味子、白术、山栀炒、白芍各10g,甘草、大黄各8g,柴胡6g;阳黄身热加茵陈蒿12g,栀子、大黄各9g);②气滞血瘀,舒肝理气通补方(香附、陈皮、枳实、防风、赤白芍、茵陈、五味子、丹参各10g,甘草8g,川芎、鳖甲粉、柴胡各6g;血虚、血瘀加熟地、当归各15g,白芍10g,桃仁9g,红花6g);③肝肾阴虚,补肾固精方(郁金、茵陈、当归、麦冬、白芍、防风、沙参、生地、川楝子、五味子、郁金各10g,甘草8g);④肝郁脾虚,健脾疏肝方(扁豆、山药各15g,防风、茯苓、郁金、当归、茵陈、白芍、五味子、白术各10g,甘草8g,柴胡6g;头痛目眩,口燥咽干加生姜15g,薄荷、甘草炙各6g);上方均1剂/d,水煎400mL,早晚口服。连续治疗90d为1疗程。观测临床症状、中医症候积分、肝功能指标、不良反应。连续治疗3疗程,判定疗效。[结果]治疗组显效15例,有效9例,无效6例,总有效率80.00%。对照组显效6例,有效12例,无效12例,总有效率60.00%。治疗组疗效优于对照组(P<0.05)。中医症候积分改善治疗组优于对照组(P<0.05)。肝功能指标两组均有改善(P<0.05),治疗组改善优于对照组(P<0.05)。[结论]辨证治疗自身免疫性肝炎效果显著,值得推广。
[ Objective ] To observe the efficacy of dialectical treatment of autoimmune hepatitis. [ Methods] Random parallel control method, 60 cases of inpatient and outpatient treatment order numbers were divided into two groups. The control group 30 cases of glycyrrhizin diammonium capsules, 150mg / time, 3 times / d, orally;hilirubin plus Yinzhihuang particles, 6g / time, 3 times / d, orally. Treatment group of 30 patients (1) heat Accumulation, clearing heat side (Yiyiren, Yichen 30g, Shanyao 15g, Huanghui, Fanfeng, Wuweizi, Baizhu, Shanzhi fried, Baishao 10g, Gancao, Dahuang each 8g, Chaihu 6g;sun yellow fever plus Yinchenhaol2g, Zhizi, Dahuang9g ) ; (2)blood stasis, liver qi up side ( Xiangfu, Chenpi, Jishi, Fanfeng, Chibaishao, Wuweizi, Danshen each lOg, Gancao 8g, Xhuanxiong, Biejiafen, Chaihu each 6g;deficiency, blood stasis plus Shudi, Dangui 15g, Baishao 10g, Taoren 9g, Honghua 6g ) ; (3) liver and kidney, Bushengubiao Jing Fang (Yujin, Yinchen, Dangui, Maidong, Baishao, Fanfeng, Shashen, Shengdi, Chuanlianzi, Wuweizi, Yujin each 10g, Gancao 8g ); (4) liver spleen, liver and spleen Fang ( Biandou, Shanyao each 15g, Fanfeng, Fuling, Yujin, Dangui, Yinchrn, Baishao, Wuweizi, Baizhu each 10g, Ganeao 8g, Chaihu 6g;headache, dizziness, dry mouth and throat add Shengjiang 15g, Bohe, Gancao fried each 6g ) . The above herbs are 1 / d, decoction 400mL, sooner or later orally. 90d is a continuous course of treatment. Observation of clinical symptoms, symptom scores, liver function, adverse reactions. Continuous treatment for 3 courses, 1o determine efficacy. [ Results ] 15 cases markedly effective in 9 cases, 6 cases, the total efficiency of 80.00%. The control group that were 6 cases, effective in 12 cases, 12 cases, the total efficiency 60.00%. Treatment group than the control group ( P〈0.05 ) . Symptom scores in treatment group than the control group ( P〈0.05 ) .Liver function improvement in the treatment group ( P〈0.05 ), improvement in the treatment group than the control group ( P〈0.05 ) . [ Conclusion ] Differential Treatment of autoimmune hepatitis effect is significant, it is worth promoting.
出处
《实用中医内科杂志》
2014年第5期42-44,共3页
Journal of Practical Traditional Chinese Internal Medicine
关键词
自身免疫性肝炎
清利湿热方
舒肝理气通补方
补肾固精方
健脾疏肝方
甘草酸二铵胶囊
茵栀黄颗粒
随机平行对照研究
Autoimmune hepatitis
Shugan qi up party
Kidney Gujing party
Spleen and liver side
Diammonium Glycyrrhizinate capsules
Yinzhihuang particles
Randomized parallel group study of clearing heat party