芪桂生肌膏湿敷联合西药干预糖尿病足血管介入术后恢复随机平行对照研究

Qi Gui Ointment Wet Joint Western Intervention Endovascular Treatment of Diabetic Foot Postoperative Recovery Randomized Parallel Group Study

[目的]观察芪桂生肌膏湿敷联合西医干预糖尿病足血管介入术后恢复疗效。[方法]使用随机平行对照方法,将80例住院患者按抛硬币法分为两组。对照组40例降糖药控制血糖至正常范围,控制血压,使用抗生素,血管介入干预。治疗组40例芪桂生肌膏(黄芪、桂枝各30g,川芍、当归、牛膝各20g,红花、参三七、鸡血藤各10g),研成颗粒,麻油调糊,创面清创消毒,将调好的药糊滩涂在无菌纱条上,厚约2mm,湿敷在患肢溃疡部,包扎固定,1次/2d换药;下次换药时先清洗残余药渣,重新清创消毒,敷药原则先远后近,先软后韧,先易后难,若创面渗液过多,用纱条引流;西医干预同对照组。连续治疗7d为1疗程。观测临床症状、溃疡创面、踝肱指数、不良反应。连续干预4疗程,判定疗效。[结果]治疗组显效28例,有效10例,无效2例,总有效率95.00%。对照组显效21例,有效8例,无效11例,总有效率72.50%。治疗组疗效优于对照组(P<0.05)。溃疡创面愈合及踝肱指数治疗组优于对照组(P<0.05)。[结论]芪桂生肌膏湿敷联合西医干预糖尿病足血管介入术后恢复效果显著,值得推广。

[ Objective ] Qi Gui Ointment wet Western intervention in diabetic foot joint intervention efficacy of endovascular treatment of postoperative recovery. [ Methods ] Random parallel control method, 80 cases of hospitalized patients were divided into two groups by a coin toss. Control group of 40 cases of oral or injectable antidiabetic drugs to control blood sugar to the normal range, control of blood pressure, the use of antibiotics, interventional endovascular intervention. Qi Gui intervention group of 40 patients Ointment （ Huangqi, Guizhi each 30g, Chuanshao, Dangui, Niuxi each 20g, Honghua, Shensanqi, Jixueteng 10g）, research into particles into a paste with sesame oil like, wound debridement and disinfection routine, will bring good medicine paste shoals on sterile gauze, thickness 2mm, wet limb ulcers in the Ministry bandage fixed, 1 / 2d dressing;dressing before the next cleaning residual dregs, debridement and disinfection again, dressing in principle the first distant past, after the first soft and tough, easy to difficult, if excess wound exudate, with gauze drainage ; Western intervention with the control group. 7d is a continuous course of treatment interventions. Observation of clinical symptoms, ulcer healing and ankle -brachial index, adverse reactions. 4 continuous treatment intervention to determine efficacy. E Results ] Intervention group that were 28 cases, 10 cases, 2 cases, the total efficiency of 95.00%. The control group that were 21 cases, 8 cases, 11 cases, the total efficiency 72.50%. The efficacy of the intervention group than the control group （ P〈0.05 ） . Ulcer healing and ankle-brachial index in the intervention group than the control group （ P 〈0.05 ） . [ Conclusion ] Qi Gui Ointment wet joint Western intervention endovascular treatment of diabetic foot postoperative recovery effect is significant, it is worth promoting.