86例空腹血糖受损的干预研究

Study on the interventions of the patients with abnormal impaired fasting glucose

目的研究依托健康管理手段、凭借生活方式干预,对空腹血糖受损人群预后的作用。方法在某高校职工健康体检中筛选出86例空腹血糖受损者作为研究对象,随机分成干预组和对照组,分别为44例和42例。对照组只做体检后常规健康建议;干预组在对照组基础上,应用健康管理手段实施综合干预措施,每3个月访视一次,包括提供健康教育、饮食处方、运动方案等等。1年后,经统计学处理,分析并比较2组之间和研究前后相关危险因素变化和空腹血糖受损转归情况。结果干预组的体重指数、空腹血糖、甘油三酯与对照组及干预前比较差异均有统计学意义(P<0.05);干预组75.0%(33/44)空腹血糖恢复正常,6.8%(3/44)发展为显性糖尿病,而对照组33.3%(14/42)空腹血糖恢复正常,19.1%(8/42)发展为显性糖尿病,2组空腹血糖恢复正常比较(χ2=11.60)以及2组发展为显性糖尿病比较(χ2=5.62)差异均有统计学意义(P<0.05)。结论健康管理手段能有效改善空腹血糖受损人群的转归,值得在单位职工健康体检中推广。

Objective To study the prognosis of impaired fasting glucose（IFG） through health management tools and lifestyle interventions. Methods We selected the faculties of a college in the health examination as the research object.Eighty six cases of IFG were randomly divided into two groups,control group with forty two cases and intervention group with forty four cases. The patients in the control group were given conventional treatment,and the patients in the intervention group received standardized comprehensive interventions every three months,which include health education,diet prescription,movement programme,and so on. The change of multiple risk factors was observed and compared between the two groups before and after the interventions one year ago. Data were statistically analyzed. Results The differences in the comparison of the observed indicators（ body mass index,IFG and triglycerides） were statistically significant between the two groups after the interventions（P〈0. 05） and compared with those before the interventions（P〈0. 05）. In the intervention group,75%（33 /44） cases returned to normal fasting glucose,and 6. 8%（3 /44） cases developed overt diabetes. However,in the control group,33. 3%（14 /42） cases returned to normal fasting glucose,while 19. 1%（8 /42） cases developed overt diabetes. The comparison of the observed fasting blood sugar back to normal（χ^2= 11. 60,P〈0. 05） and the developed into overt diabetes（χ^2= 5. 62,P〈0. 05） showed a significant difference between the two groups after the interventions. Conclusion Health management tools in IFG cases can effectively improve the prognosis of IFG. And if the way was widely received by the faculties with IFG in the health examination,it can prevent them from suffering diabetes.