摘要
目的研究特发性尿毒症患者腹水感染病原菌的种类及耐药情况,为临床合理用药提供参考。方法通过回顾性调查,对某医院特发性尿毒症患者腹水标本细菌分离鉴定及药敏试验结果进行调查与分析。结果从病人腹水标本中共分离到病原菌128株,其中革兰阴性杆菌占59.4%;居前三位的细菌分别为大肠埃希菌、肺炎克雷伯菌和粪肠球菌,构成比依次为28.1%、11.7%和10.2%。大肠埃希菌对青霉素类、头孢类和喹诺酮类抗菌药物有较高的耐药率;肺炎克雷伯菌和粪肠球菌对大部分抗菌药物比较敏感。结论特发性尿毒症患者腹水感染的病原菌以产超广谱β内酰胺酶的大肠埃希菌为主,对临床常用抗菌药物普遍耐药。
Objective To research types and drug resistance of idiopathic uremic ascites pathogens, and provide reference for clinical rational drug use. Method Retrospective survey was used to analyze the results of identification and susceptibility testing of idiopathic uremic ascites specimens in a hospital. Results 128 strains of pathogens were isolated, Gram - negative bacilli accounted for 59.4%. The top three bacteria were Escherichia coli （28.1% ）, Klebsiella pneumoniae （11.7%） and Enterococcus faecalis （10. 2% ）. The resistance rates of Escherichia coli to penicillins, cephalosporins and quinolones were high. Klebsiella pneumoniae and Enterococcus faecalis were sensitive to most antimicrobial agents. Conclusion Idiopathic uremic ascites infection was pathogens mainly producing extended - spectrum β - lactamase Escherichia coil The bacteria is generally resistant to commonly antimierobial agents.
出处
《中国消毒学杂志》
CAS
北大核心
2014年第7期689-691,共3页
Chinese Journal of Disinfection
关键词
尿毒症
腹水
医院感染
病原菌
耐药性
uremic
ascites
hospital infection
pathogens
drug resistance
