布鲁菌病172例流行病学特点及临床分析

Epidemiological and clinical study of 172 cases of Brucellosis

目的：总结布鲁菌病的临床特点，探讨布鲁菌病诊断及治疗经验。方法回顾性分析布鲁菌病172例患者的临床资料，总结患者的流行病学资料、临床表现及辅助检查的特点。结果130例患者获得确诊，发生误诊42例，其中误诊为腰椎病变13例，呼吸道感染10例，血细胞减少8例，睾丸炎附睾炎5例，肝炎2例，前列腺炎1例，颈椎病1例，心肌炎1例，类风湿关节炎1例。治疗后症状完全消失142例，好转16例，总有效率100．0％。复发2例，时间为3～15个月（均为未规范用药者）。结论布鲁菌病的临床表现缺乏特异性，误诊率高；早期规范的抗菌素联合治疗可获得较好疗效。

Objective To summarize the clinical features of brucellosis and investigate the experience of diagnosis and treatment of the disease .Methods Data from epidemic reports and clinical characteristics from 172 ca-ses of patients with brucellosis were retrospectively analyzed .Results 130 out of 172 cases of were diagnosed as bru-cellosisaise.Of the misdiagnosed 42 cases,13 cases were misdiagnosed as lumbar spine ,10 cases as upper respiratory tract infection 8 cases as pancytopenia,5 cases as orchitis epididymitis,2 cases as hepatitis,1 case as prostatitis, 1 case as cervical disease ,1 case as myocarditis ,1 case as rheumatoid arthritis .And after treatment ,142 cases recov-ered completely,16 cases improved.The total efficiency was 100.0%.2 cases without standard treatment recurred ,an interval of 3 to 15 months.Conclusion So the clinical manifestation of brucellosis is lack of specificity that misdiag-nosis rate is high;The manipulation combined with standard antibiotic therapy may have certain effects on early -stage brucellosis .