中毒性肝炎型毒蕈中毒17例临床分析

Characteristics and treatment methods of 17 cases toxic hepatitis type mushroom poisoning patient

目的：分析中毒性肝炎型毒蕈中毒的发生和临床表现，探讨中毒性肝炎型毒蕈中毒的治疗方法。方法选取中毒性肝炎型毒蕈中毒患儿共17例，对其进行回顾性临床分析。结果17例中毒性肝炎型毒蕈中毒患儿经药物治疗后，痊愈12例，死亡5例，痊愈率70．6％；所有患儿的红细胞、白细胞及血红蛋白均正常，7例出现便血，6例出现血尿，所有患者肝功能检查转氨酶及黄疸指数均明显升高，心电图示窦性心动过缓8例，窦性心动过速2例，1例出现肾功能损害。结论中毒性肝炎型毒蕈中毒病死率较高，彻底清除毒物是救治关键，血浆置换治疗有一定疗效，肝移植是最有效的治疗手段。

Objective To analyze the clinical feature of 17 cases children toxic hepatitis type of mushroom poisoning ,investigate toxic hepatitis type mushroom poisoning treatment .Methods 17 children with mushroom poi-soning toxic hepatitis were chosen as the objects of study ,who were retrospectively analyzed .Results 17 cases of tox-ic hepatitis type of mushroom poisoning in children were dealed with drug treatment ,cured 12 cases,5 deaths,the cure rate of 70.6%;all patients,red blood cells,white blood cells and hemoglobin were normal ,7 cases of blood in the stool,6 cases of hematuria .All patients transaminase liver function tests and jaundice index were significantly in-creased,electrocardiogram showed sinus bradycardia 8 cases, sinus tachycardia 2 cases,1 case of renal damage. Conclusion Toxic hepatitis type mushroom poisoning mortality ,the elimination of toxins is where the key to have a certain effect of plasma exchange therapy ,liver transplantation is the most effective means of treatment ,especially gas-trointestinal bleeding with liver damage ,should be carried out as soon as possible based treatment plasmapheresis .