黔南地区苗族与汉族早期宫颈癌患者临床病理特点和预后影响因素

Clinicopathological characteristics and influencing factors of prognosis in early cervical cancer patients of Miao nationality and Han nationality in Qiannan region

目的：探讨黔南地区苗族与汉族早期宫颈癌患者临床病理特点和预后影响因素,为黔南地区宫颈癌的防治提供参考依据。方法：选择2003年1月~2009年12月黔南地区的宫颈癌患者89例,按民族分为苗族组（48例）和汉族组（41例）,比较两民族患者临床病理特点和预后影响因素。结果：苗族组接触性出血、阴道不规则出血、白带增多病例数、病程发生时间、年龄、产次、肿瘤大小、病理类型、淋巴结转移、浸润深度、HPV感染病例数、5年生存状况、中位生存期及2年内复发病例与汉族组比较,差异均有统计学意义（P〈0.01）;产次、病理类型、宫颈间质浸润深度、淋巴结转移、肿瘤大小及临床分期为5年生存状况的影响因素,差异有统计学意义（P〈0.05）。结论：不同民族宫颈癌患者临床病理特点和预后影响因素存在差异,临床诊疗中应重视对民族特性的了解,强调早期和个体化诊治。

Objective： To explore the clinicopathological characteristics and influencing factors of prognosis in early cervical cancer patients of Miao nationality and Han nationality in Qiannan region, provide reference for prevention and treatment of cervical cancer in Qiannan region. Methods： Eighty - nine patients with cervical cancer were selected from Qiannan region from January 2003 to December 2009, then the patients were divided into Miao nationality group （48 patients ） and Han nationality （41 patients） according to nationality; the clinicopathological characteristics and influencing factors of prognosis in the two groups were compared. Results： There were statistically significant differences in the numbers of contact bleeding, irregular vaginal bleeding and leucorrhea increase, the course of disease, age, parity, tumor size, pathological types, lymph node metastasis, depth of invasion, the numbers of HPV infection, five - year survival rate, median survival time and number of recurrent patients within two years between the two groups （P 〈 0. 01 ） ; parity, pathological types, depth of cervical invasion, lymph node metastasis, tumor size and clinical stages were influencing factors of five - year survival rate, there were statistically significant differences （P 〈 0.05） . Conclusion： There are differences in clinicopathological characteristics and influencing factors of prognosis in early cervical cancer patients of different nationalities, more attention should be paid to ethnic characteristics, early and individual diagnosis and treatment during clinical diagnosis and treatment.