身高标化细胞外液在评估CAPD患者容量负荷及心肌重构中的价值

The value of normalized extracellular fluid volume by body height in the estimation of volume overload and ventricular remodeling in patients with continuous ambulatory peritoneal dialysis

目的探讨身高标化细胞外液(ECW∕h)在评估CAPD患者容量负荷及心肌重构中的价值。方法收集CAPD患者人体成分分析、心脏超声等资料。分析ECW∕h与心脏容量负荷及心肌重构的相关性;不同ECW∕h组患者心脏容量负荷及心肌重构的差异。结果相关分析显示,CAPD患者ECW∕h与心脏容量负荷指标LVEDD及LAD呈显著正相关(r=0.507,0.492,P<0.001);与心肌重构指标LVPWT、LVM、IVST及LVMI呈显著正相关(r=0.463,0.581,0.403,0.404,P<0.001)。ECW∕h>9.04 L∕m组患者心脏容量负荷指标LVEDD及LAD显著高于ECW∕h<9.04L∕m组患者(P<0.01);ECW∕h>9.04 L/m组患者心肌重构指标IVM、IVST、LVPWT及LVMI显著高于ECW∕h<9.04L∕m组(P<0.05)。结论 ECW∕h在评估CAPD患者容量负荷及心肌重构中有一定的临床价值。

Objective To explore the value of normalized extracellular fluid volume by body height （ECW/h） in the estimation of volume overload and ventricular remodeling in patients with continuous ambulatory peritoneal dialysis （CAPD）. Methods Data about body composition and echocardiography were collected and used to analyze the correlation of ECW □ h with volume overload and ventricular remodeling. We also analyzed the differences of volume overload and ventricular remodeling in patients with ECW/h 〉9.04 L/m and those with ECW/h〈9.04L/m. Results Pearson＇ s analysis showed that ECWSh was positively correlat ed with the volume load parameters of LVEDD and LAD （1=0.507 and 0.492, respectively; P〈0.001） and the ventricular remodeling parameters of LVPWT, LVM, IVST and LVMI （r =0.463, 0.581, 0.403 and 0.404, respectively; P〈0.001. Volume overload and ventricular remodeling indicators including LVEDD, LAD, LVP- WT, LVM, IVST, and LVMI were higher in patients with ECW/h〉9.04 L/m than in those with ECW/h〈 9.04L/m. Conclusion ECW/h is valuable in the clinical evaluation of volume overload and ventricular remodeling in CAPD patients.