参苓白术散干预糖耐量异常患者的临床疗效

Clinical Effect of Shenling Baizhu Powder to Treat Patients with Abnormal Glucose Tolerance

目的:对使用参苓白术散来干预糖耐量异常患者的临床疗效进行观察分析。方法:82例糖耐量异常患者,随机分成对照组和治疗组,对照组给予饮食、运动指导,治疗组在对照组的基础上给予参苓白术散治疗,给药前和连续给药24周后,分别检测患者空腹血糖、餐后2 h血糖、空腹胰岛素、糖化血红蛋白、总胆固醇、三酰甘油、高密度脂蛋白、低密度脂蛋白。结果:随访24周后,参苓白术散治疗组总有效率79.1%;对照组总有效率53.8%,治疗组与对照组比较,总有效率差异有统计学意义(P<0.05);治疗组的餐后2 h血糖显著性下降(P<0.05)。结论:参苓白术散能有效控制糖耐量异常进展,在临床实践中体现中医治未病的意义。

To study the clinical curative effects of Shenling Baizhu powder to treat patients with abnormal glucose tolerance. Methods：Eighty two patients with abnormal glucose tolerance were randomly separated into control group and intervention group.Patients in the control group were given guidance of diets and exercises and the intervention group extra applied shenling baizhu powder. Before and after continuous treatment for 24 weeks,the levels of FPG,2 hPG FINS,HbA1 C,TC,TG,HDL and LDL were detected. Results：After 24 weeks of treatment,21 out of 43 cases （48.8%）were cured in the intervention group and the total effective rate was 79.1%;while in the control group only 6 out of 39 patients （1 5.4%）were cured,and the total effective rate was 53.8%,which was lower than the intervention group and the total effective rate difference was statistically significant （χ2 =5.892,P=0.015）.Conclu-sion：Shenling baizhu powder can effectively control the progress of abnormal glucose tolerance limit,which reflects the significance of Chinese traditional medicine theory of＆quot;treat pre-disease＆quot;in the clinical practice.