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糖皮质激素治疗体外循环心脏术后全身炎性反应的研究进展 被引量:6

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摘要 体外循环技术的出现使各类心脏直视手术成为可能。然而,由于体外循环过程中血液与人工心肺机的非生理性表面接触、缺血再灌注损伤以及内毒素的释放等因素,引起炎性因子激活以及剧烈的全身炎症反应,可导致心脏术后并发症发生率升高以及死亡率增加。糖皮质激素具有明确和强大的抗炎作用,近年来已有多项基础和临床研究证实了其对体外循环术后炎性反应的控制效果和作用机制。该文对近年来糖皮质激素应用于体外循环的相关研究进行回顾和总结。
作者 王杨 徐志云
出处 《国际心血管病杂志》 2014年第4期243-245,255,共4页 International Journal of Cardiovascular Disease
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