卵巢恶性肿瘤影响因素的病例对照研究

The influencing factors of ovarian cancer: A case-control study

目的 研究影响卵巢恶性肿瘤发生的因素,为有效预防和治疗疾病提供理论依据.方法 采用病例对照研究的方法收集我院2010年6月～2013年8月诊断治疗卵巢恶性肿瘤患者的资料,并收集同期住院的非恶性肿瘤患者资料作为对照,评估相关影响因素,构建多元Logistic回归模型.结果 痛经史（OR=1.681,95％CI：1.103～3.148）、人工流产史（OR=1.524,95％CI：1.156～3.640）、月经初潮年龄＜13岁（OR=2.442,95％CI：1.197～4.387）和肿瘤家族史（OR=3.961,95％CI：1.336～5.718）是卵巢恶性肿瘤发生的独立危险因素.结论 卵巢恶性肿瘤的发生与女性月经、人工流产、家族史等有密切关系,对于重点高危人群应加强监察,早发现、早诊断、早治疗.

Objective To study influencing factors of ovarian cancerand provide the knowledge for preventing it. Methods The case-control study method was＇used to search the message from July, 2010.to August, 2013. The Logis- tic regression model was used to assess the influencing factors. Results The results showed that dysmenorrhea history （OR=1.681,95%CI： 1.103-3.148）, history of induced abortion （0R=1.524,95%CI： 1.156-3.640）,age of menarche （OR=2.442, 95%CI： 1.197-4.387） and family history of cancer （OR--3.96!,95%CI： 1.336-5.718） were independent risk factor toovarian cancer. Conclusion There were closely related between ovarian cancer and women menstruation, abortion, family history, so it is impartment to take early detection, early diagnosis and early treatment.