门冬胰岛素联合甘精胰岛素治疗小儿1型糖尿病护理观察

The nursing observation of insulin aspart and insulin glargine in the treatment of pediatric typeⅠdiabetes of children

目的 探讨门冬胰岛素联合甘精胰岛素治疗小儿1型糖尿病的疗效及护理措施.方法 选取2011年10月～2013年10月我院收治的小儿1型糖尿病患儿69例,分为观察组（35例）和对照组（34例）,对照组单纯给予门冬胰岛素治疗,观察组予门冬胰岛素联合甘精胰岛素治疗,并加强护理工作,比较两组患儿实验室检查指标以及低血糖发生率.结果 观察组空腹血糖（FBG）、餐后2h血糖（2 hBG）、糖化血红蛋白（HbA1c）、甘油三酯（TG）、胆固醇（TC）等实验室相关指标改善均优于对照组（P＜0.05）,且观察组低血糖发生率显著低于对照组（P＜0.05）,两组患儿的护理质量评分比较,差异有统计学意义（P＜0.05）.结论 门冬胰岛素联合甘精胰岛素治疗小儿1型糖尿病疗效确切,同时通过加强护理工作,能显著提高临床治疗效果,降低低血糖发生.

Objective To investigate the efficacy and nursing measures of insulin aspart and insulin glargine in the treatment of pediatric type I diabetes of children. Methods A total of 69 cases of children with infantile type I dia- betes from October 2011 to October 2013 of our hospital were divided into observation group （35 cases） and control group （34 cases）. The control group was simply given insulin aspart, the observation group was given insulin aspart and insulin glargine combined with strengthening nusing care. The laboratory parameters and the incidences of hypo- glycemia of the two groups of children were compared. Results The laboratory related parameters such as fasting plas- ma glucose （FBG）, 2 h postprandial blood glucose （2 hBG）, glycosylated hemoglobin （HbAlc）, triglyceride （TG） and cholesterol（TC） of the observation group were better than those of the control group（P〈0.05）, the incidence of hy- poglycemia in the observation group was significantly lower than the control group. The nursing quality scores of the two groups were significantly different, which had statistically significant （P〈0.05）. Conclusion By strengthening the nursing work, insulin aspart combined with insulin glargine can significantly improve clinical treatment effects and re- duce the incidence of hypoglycemia in the treatment of pediatric type I diabetes of children.