脂蛋白(a)与脂肪肝相关性探讨

The correlation analysis between the lipoprotein(a) and fatty liver

脂肪肝是多种肝脏疾病发展中的一种病理过程,其发病的诱因比较多,而在病理变化中主要为肝细胞内甘油三脂蓄积过多。从脂肪肝发病的机制上来说,脂肪肝是由于输入肝脏的脂肪及脂肪酸过多、肝脏合成脂蛋白障碍和脂肪酸在肝氧化不足导致脂蛋白(a)表达过高所致。本文概述了脂肪肝与脂蛋白(a)的临床现状,分析了脂肪肝的发病机制,探讨了脂肪肝与脂蛋白(a)的相关性,提出了基于脂蛋白(a)的脂肪肝预防干预措施。

Liver Fatty liver disease is the development of a variety of a pathological process, the incidence of more centives, the main pathological changes in the excessive accumulation of triglycerides in the liver cells. From the mechanism of fatty liver disease, the fatty liver due to excessive input of fat and fatty liver, liver disorder lipoprotein synthesis and fatty acid oxidation in the liver leads to lack of lipoprotein （a） the expression is too high. This paper begins with an overview of the clinical status of fatty liver and lipoprotein（a）, the analysis of the pathogenesis of fatty liver, fatty liver and discussed liPoProtein （a） the correlation is proposed based on fatty liver lipoprotein （a） prevention interventions.