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金属离子对喹诺酮活性影响的研究进展 被引量:3

Research Progress of Metal Ions Influence The Activity of Quinolone
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摘要 喹诺酮类药物以抗菌活性强、抗菌谱广、疗效确切等优点被广泛应用于临床,一些研究结果表明金属离子对喹诺酮类药物的活性有一定的影响。本文概述了喹诺酮类药物的发展及作用机制,总结了金属离子对喹诺酮类的作用及喹诺酮类药物金属配合物的活性,最后展望了喹诺酮类药物今后的发展。 Quinolone are widely used clinically because of its antibacterial activity, widely spectrum antimicrobial, curative effect, etc.Some studies show that the metal ions affect the activity of quinolone.This paper outlines the development and action mechanism of quinolone. Summarizes the role of metal ions on metal quinolone and the biological activity of quinolone complexes. Finally, prospects of the development of quinolone.
出处 《黑龙江医药》 CAS 2014年第4期801-804,共4页 Heilongjiang Medicine journal
基金 黑龙江省教育厅科学技术研究项目 项目编号:12511511
关键词 喹诺酮类药物 作用机制 金属离子 生物活性 Quinolone Action mechanism Metal ions Biological activity
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