摘要
目的:建立小儿咳喘灵口服液微生物限度检查法,并对方法进行验证。方法:将供试品配制1:10的溶液,按常规法进行细菌数、霉菌和酵母菌数检查及控制菌(大肠埃希菌)的检查。结果:在3批样品独立的平行试验中,细菌数、霉菌和酵母菌数检查方法的验证试验,5株试验菌回收率均大于70%;控制菌检查中,检查大肠埃希菌,试验组均可检出试验菌,阴性组均无菌生长,阴性菌对照组均无菌生长。结论:采用常规法对该品种进行细菌数,霉菌和酵母菌计数及控制菌检查,方法有效可行。
Objective: To establish a method for the microbial limit test of Children Kechuan oral liquid. Methods:The sample preparation of 1:10 solution, bacteria, yeast and mold counts the number of inspection and control bacteria by conventional method (Escherichia coli)examination. Results:In the parallel test of Three batches of samples, verification test bacteria, yeast and mold count number check method, 5 strains of tested bacteria recovery rate was more than 70%;The control bacteria examination determination, Escherichia coli, the test group were detected bacteria, negative group are sterile growth, Gram-negative bacteria in the control group had no growth. Concluslon:The number of bacteria by routine method, molds and yeasts count and control bacteria examination,effec-tive and feasible method.
出处
《黑龙江医药》
CAS
2014年第4期806-808,共3页
Heilongjiang Medicine journal