基于《中医针灸信息库》对针灸治疗抑郁症多因素分析

Multifactor Analysis of Acupuncture-moxibustion Treatment for Depression on the Basis of “Traditional Chinese Medical Acupuncture-moxibustion Information Database”

目的 回顾2004年至2013年针灸文献,探索提高针灸治疗抑郁症的临床疗效.方法 根据《中医针灸信息库》,采用计量分析、单因素方差分析和t检验对针灸治疗抑郁症的常用穴位、常用治疗方法、治疗次数、HAMD值、疾病程度、不同病因进行多因素分析.结果 经多因素分析证实中度抑郁症是针灸治疗的适宜证;治疗次数以11～20次为宜;百会、内关应用频次为最高,百会配内关、太冲,百会配内关、三阴交可作为最佳配穴;治疗方法以针刺为主,单纯电针疗法和单纯针灸疗法临床疗效优于单纯氟西汀,针灸配合氟西汀可提高临床疗效.结论 针灸治疗抑郁症有较好的疗效.

Objective To investigate and improve the clinical therapeutic effect of acupuncture and moxibustion on depression by reviewing acupuncture-moxibustion literature published from 2004 to 2013.Methods On the basis of＂Traditional Chinese medical acupuncture-moxibustion information database＂,an analysis of multiple factors including commonly used acupoints,commonly used therapeutic methods,number of treatments,HAMD value,disease severity and different etiologies in acupuncture-moxibustion treatment for depression was made by bibliometric analysis,single factor analysis of variance and a t-test.Results A multifactor analysis shows that moderate depression is suitable for acupuncture-moxibustion treatment.The proper number of treatments is from 11 to 20.Baihui and Neiguan are the most frequently used points.Baihui plus Neiguan and Taichong,and Baihui plus Neiguan and Sanyinjiao can be used as the optimal point combinations.Acupuncture is the main therapeutic method.The clinical therapeutic effect of electroacupuncture alone or acupuncture-moxibustion treatment alone is better than that of fluoxetine alone.Acupuncture and moxibustion plus fluoxetine can improve the clinical therapeutic effect.Conclusion Acupuncture-moxibustion treatment has a good effect on depression.