穴位贴敷对慢性疲劳综合征疲劳及内分泌功能的影响

Effect of Acupoint Sticking on Chronic Fatigue Syndrome and Endocrine Function

目的观察加味四逆散穴位贴敷五脏背俞穴对肝郁脾虚型慢性疲劳综合征(CFS)患者疲劳症状及内分泌功能的影响。方法将60例符合纳入标准的患者随机分为治疗组和对照组,每组30例。治疗组采用五脏背俞穴行针刺配合穴位贴敷治疗,对照组采用五脏背俞穴行单纯针刺治疗,对比治疗前后患者疲劳量表-14(FS-14)、自拟肝郁脾虚型CFS症状分级量表的积分及血清促肾上腺皮质激素(ACTH)、血清总皮质醇(CORT)的变化。结果两组治疗后FS-14评分、症状分级量表评分、血清ACTH及CORT含量与同组治疗前比较,差异均具有统计学意义(P<0.05)。治疗组治疗前后FS-14评分、症状分级量表评分、血清ACTH及CORT含量差值与对照组比较,差异均具有统计学意义(P<0.05)。治疗组总有效率为85.2%,对照组为60.7%,两组比较差异具有统计学意义(P<0.05)。结论加味四逆散贴敷五脏背俞穴能够有效地改善肝郁脾虚型CFS患者的疲劳症状,并改善患者的内分泌功能。

Objective To observe the effect of acupoint sticking at Back-Shu points with modified Si Ni powder on fatigue symptoms and endocrine function in chronic fatigue syndrome （CFS） due to liver depression and spleen deficiency.Methods Sixty eligible subjects were randomized into a treatment group and a control group,30 in each group.The treatment group was intervened by acupuncture plus acupoint sticking at the Back-Shu points,while the control group was only by acupuncture at the Back-Shu points.The following items were observed and compared before and after intervention：fatigue scale 14 （FS-14）,self-made CFS （liver depression and spleen deficiency type） symptom grading scale,serum ACTH and CORT contents.Results After intervention,the FS-14,CFS symptom grading scale,serum ACTH and CORT contents were changed significantly in both groups （P＜0.05）.The changes of FS-14,symptom grading scale,serum ACTH and CORT in the treatment group were markedly different from those in the control group （P＜0.05）.The total effective rate was 85.2％ in the treatment group versus 60.7％ in the control group,and the difference was statistically significant （P＜0.05）.Conclusion Acupoint sticking at Back-Shu points with modified Si Ni powder can effectively improve the fatigue symptoms and endocrine function of the CFS patients due to liver depression and spleen deficiency.