倍他洛尔滴眼液在视网膜中央动脉阻塞治疗中应用疗效观察

Therapeutic effect of betaxolol on central retinal artery occlusion

目的观察倍他洛尔眼药水局部使用在治疗视网膜中央动脉阻塞(CRAO)中的临床效果。方法临床确诊视网膜中央动脉阻塞患者34例(34眼),在联合葛根素等常规治疗不变的情况下,随机按使用倍他洛尔眼水有无,分为倍他洛尔治疗组及对照组进行一个月疗程的治疗,观察并记录治疗前后视力、视野、闪光视网膜电图及眼压的变化情况。结果两组间视野检查平均敏感度提高、视网膜电图b波幅度提高、眼压差值有差异;治疗组视力提高较明显,但有效率与对照组无显著差异。结论倍他洛尔眼水局部应用联合常规疗法治疗视网膜中央动脉阻塞,可提高临床效果,有一定的治疗意义。

Objective To observe the therapeutic effect of Betaxolol on central retinal artery occlusion（CRAO）.Methods 34 patients（34 eyes） who were diagnosed as with CRAO,were divided into the treatment group and control group.Betaxolol was applied to treatment group.All patients underwent other conventional therapy at the same time,and the period of treatment lasted for one month.Visual activity,visual field,bright-flash electroretinogram（ERG） and intraocular pression（IOP） of all patients were observed at the beginning of therapy and followed up.Results After 1 month,The change of Visual activity was seen to be better in the treatment group,but the difference was not significant（P〉 0.05）.The mean sensitivity（MS） of visual field,the amplitudes ERG b-wave recovery and the change of IOP were higher in the in the treatment group than in the control group（P〈0.05）.Conclusion Betaxolol is efficacious in treatment of CRAO.