2013年某院临床常见病原菌分布特点及耐药性分析

Distribution characteristics of common pathogens and resistance analysis of 2013

目的分析2013年我院临床常见病原菌的分布特点及其对常见抗菌药物的耐药情况,为临床合理用药提供参考。方法利用VITEK-2全自动微生物分析仪和ATB自动微生物分析系统进行病原菌鉴定和药敏试验。结果5394株病原菌中,革兰氏阴性菌占53.58%,革兰氏阳性菌占23.88%,真菌占11.49%;大肠埃希菌、铜绿假单胞菌和肺炎克雷伯菌排在革兰氏阴性菌检出率的前三位,分别为:18.97%、12.44%、8.64%。MRSA和MRCNS的检出率是35.27%和81.37%。结论病原菌多重耐药情况严重,应引起临床高度重视。

Objective To understand distribution and drug resistance of common pathogens,so as to provide reference for the rational clinical application of antibiotics.Methods The implement identification was conducted by using VITEK-2 auto bacterial identification system,and susceptibility was tested by using susceptibility test instrument.The results were interpreted according to the standards developed by Clinical and Laboratory Standard Institute（CLSI） of the USA.Results A total of5394 strains of pathogens were isolated,including Gram-negative bacteria（53.58%）,Gram-positive bacteria（23.88%） and fungi（11.49%）.Escherichia coli,Pseudomonas aeruginosa and Klebsiella pneumoniae ranked in the top three detection rate of Gram-negative bacteria,respectively; 18.97%,12.44%,8.64%.MRSA and MRCNS detection rate was 35.27% and81.37%.Conclusion Multidrug-resistant pathogens in serious condition should lead to clinical attention.