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Igf2/H19印迹基因在辅助生殖技术(ART)早期胚胎中的作用 被引量:1

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摘要 辅助生殖技术(ART)目前成为了人们解决不孕不育的主要方式,但是通过ART出生的后代发生基因印迹改变导致表观遗传学疾病的报道出现,使得辅助生殖技术的安全性受到了人们的关注。早期胚胎发育受印迹基因的调控,而Igf2/H19基因是最早被发现的内源性印迹基因,正确的印迹对哺乳动物的胎儿和胎盘正常发育至关重要。Igf2/H19基因编码重要的印迹基因,控制正常的早期胚胎发育。Igf2/H19基因与ART早期胚胎的关系尚不十分明确,有待进一步的深入研究和探讨。
出处 《中国优生与遗传杂志》 2014年第8期6-8,共3页 Chinese Journal of Birth Health & Heredity
基金 芜湖市2009年度农社类各单位科技计划项目 卫生类-1-2
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