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基础FSH/LH比值与卵巢储备功能及IVF/ICSI治疗结局相关性的研究 被引量：3

Effect of the basal FSH and LH ratio on the ovarian reserve function and the pregnancy outcome of IVF/ICSI
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摘要 目的评价基础FSH/LH对预测基础FSH正常水平妇女IVF/ICSI-ET(体外受精-胚胎移植,In vitro fertilization-embryo transfer/卵胞浆内单精子注射-胚胎移植,Intracytoplasmic sperm injection-embryo transfer)结局的价值及其与超促排卵过程中各参数的关系。方法回顾性分析接受IVF/ICSI-ET治疗的不孕患者617例,据基础FSH/LH(Follicle-stimulating hormone,卵泡刺激素/luteinizing hormone,黄体生产素)比值分为2组:FSH/LH<2组和FSH/LH≥2组,比较两组的用药情况和临床结局。结果 FSH/LH<2组与FSH/LH≥2组相比,获卵数、受精率、着床率、临床妊娠率显著增加,Gn(GnRH,促性腺激素释放激素,以下简称Gn)用量显著减少(P<0.05)。结论基础FSH/LH值能够提早预测卵巢储备功能及IVF/ICSI治疗结局,并且能指导临床控制性超促排卵过程中用药量。 Objective- To investigate the correlation of the basal FSH and LH Ratio and the ovarian reserve function and the pregnancy outcome of in-vitro fertilization （IVF） / Intracytoplasmic sperm injection （ICSI） . Methods A retrospective analysis was performed in the Medical records of 617 patients who had underwent IVF/ICSI-ET treatment. Patients were divided into two groups according to serum basal Follicle-Stimulating Hormone （FSH） and Luteinizing Hormone （LH） concentration： FSH/LH 〈2 and FSH/LH≥2. Results Compared to FSH/LH≥2 group, the number of oocytes retrieve, fertilization rate, implantation rate, biochemical pregnancy rate and clinical pregnancy rate in the FSH/LH 〈2 group were significantly higher, and dosage of gonadotropin （Gn） was significantly lower. Conclusion： Basal FSH and LH Ratio is a good marker of the ovarian reserve function, and it also could be a predictive index of the treatment outcome of IVF/ICSI.
作者 赵萌 杨菁 吴庚香 余楠
机构地区 武汉大学人民医院
出处 《中国优生与遗传杂志》 2014年第8期115-116,89,共3页 Chinese Journal of Birth Health & Heredity
关键词 体外受精-胚胎移植(IVF-ET) FSH LH 卵巢储备功能 妊娠率 IVF-ET FSH/LH Ratio The ovarian reserve function Pregnancy rate
分类号 R714.8 [医药卫生—妇产科学]
  • 相关文献

参考文献11

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二级参考文献11

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  • 3Liu KE, Greenblatt EM. Elevated day 3 follicle-stimulating hormone/luteinizing hormone ratio ≥ 2 is associated with higher rates of cancellation in in vitro fertilization-embryo transfer cycles. Fertil Steril, 2008, 90(2):297-301.
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共引文献25

同被引文献34

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中国优生与遗传杂志
2014年 第8期

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