小剂量顺式阿曲库铵在小儿气管支气管异物取出术中的应用

Application of small-dose cisatracurium to removing the tracheobronchial foreign bodies in the trachea of children

目的:探析小剂量顺式阿曲库铵在小儿气管支气管异物取出术中的应用效果。方法:入选我院2011年10月至2013年10月择期行气管支气管异物取出术的患儿36例,根据麻醉方法不同分为两组各18例,对照组采用r-羟基丁酸钠麻醉,观察组采用小剂量顺式阿曲库铵麻醉,比较两组血流动力学情况、手术时间、术中及术后并发症发生率等。结果:两组患儿麻醉期SBP、HR及SpO2等血流动力学指标大体一致,但T1和T2时点差异有统计学意义(P均<0.05);观察组手术时间和麻醉恢复时间均短于对照组,术中及术后不良反应率均低于对照组,尤其是术中屏气和呛咳并发症低于对照组,差异均具有统计学意义(P均<0.05)。结论:小儿气管支气管异物取出术麻醉时使用小剂量顺式阿曲库铵具有稳定血流动力学、缩短手术及麻醉恢复时间和减少术中、术后不良反应等优势。

Objective. To investigate the applicative effect of small-dose cisatracurium on removing the tracheobronchial foreign bodies in the trachea of children. Methods： 36 cases of children pa tients waiting for the foreign body extraction in the trachea were divided into 2 groups with 18 in each group based on different anesthesia. The control group accepted anesthesia with rhydroxybutyric acid sodium, while the observation group were anesthetized with smalldose cisatracurium, the hemodynamics, operation time and the occurrence rate of complications in patients of both groups were compared. Results： The hemodynamic indicators of SBP, HR and SpO2 in both groups were the same, but there was significant difference of the time point between T1 and Tz （P〈0.05）; the operation and the recovery time of anesthesia of the observation group were shorter than those of the control group, the intraoperative and postoperative adverse reaction rate was lower than that of the control group, especially the complications of intraoperative breathless and choking cough was obviously lower than that of the control group, which were all of statistical difference（P〈0.05）. Conclusion： The application of small-dose cisatracurium on removing the tracheobronchial foreign bodies in the trachea of children has the advantage of stable hemodynamics, shortening the opera tion and recovery time of anesthesia, and reducing the adverse reactions.