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连续性静脉静脉血液滤过对创伤并急性肾损伤患者预后的影响 被引量:7

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摘要 目的:评价连续性静脉静脉血液滤过(CVVH)对创伤并急性肾损伤(AKI)患者预后的影响。方法:广州市第一人民医院重症医学科2003年7月至2013年6月收治的创伤并AKI患者62例,按照是否接受CVVH分为治疗组28例和对照组34例,并按AKI分期进行分层,观察患者治疗期间的血清尿素氮(BUN)、肌酐(SCr)和C反应蛋白(CRP)的变化,记录两组患者APACHEⅡ评分、尿量(UO)、氧合指数(OI)、平均动脉压(MAP)和多巴胺用量(DA)的变化,比较两组患者28 d死亡率、ICU停留时间和肾功能恢复率。结果:治疗后3 d及7 d,治疗组APACHEⅡ评分、DA、BUN、Scr和CRP均低于对照组(P<0.05);治疗后14d及28 d,治疗组APACHEⅡ评分、BUN、Scr和CRP低于对照组,UO高于对照组(P<0.05)。治疗组ICU停留时间和肾功能恢复时间明显低于对照组(P<0.05),其中2期患者28 d死亡率低于对照组,且肾功能恢复率则高于对照组(P<0.05),但两组患者28 d死亡率比较差异无统计学意义。结论:CVVH对创伤并AKI患者28 d死亡率无影响,可能有利于降低ICU停留时间和肾功能恢复时间。
出处 《实用医学杂志》 CAS 北大核心 2014年第15期2455-2458,共4页 The Journal of Practical Medicine
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参考文献13

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二级参考文献65

共引文献23

同被引文献59

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