我院2013年维生素K_1注射液的用药调查分析

Analysis of the Application of Vitamin K1Injection in Our Hospital in 2013

目的:对我院维生素K1注射液用药合理性及安全性进行分析评价。方法:收集我院2013年使用维生素K1注射液的患者672例,以药品说明书的规定为标准,参考相关书籍及文献,从维生素K1的适应证、给药剂量、给药途径、不良反应等方面进行分析。结果:我院维生素K1注射液的使用存在超适应证现象,主要存在于术后预防出血、与华法林的联合应用等方面,给药剂量基本合理,给药途径有待改进。结论:临床使用维生素K1注射液时应严格掌握适应证,选择合适的给药途径和剂量,预防药品不良反应的发生,提高用药安全性。

OBJECTIVE： To analyze and evaluate the rationality and security of the application of Vitamin K1 injection in our hospital. METHODS： 672 cases of Vitamin KI injection were collected from our hospital in 2013. Based on drug instructions, related books and documents, the indication, dosage, route of administration and ADR were analyzed. RESULTS： There was off-indica- tions medication phenomenon in the utilization of Vitamin K1 injection in our hospital, mainly in the prevention of postoperative bleeding and the combined application of warfarin. The dosage is rational on the whole, and the administration route needs to be improved. CONCLUSIONS： The indications of Vitamin K1 injection should be mastered strictly, and the dosage and the administration route should be appropriate, in order to prevent the adverse drug reactions and improve the security of drug use.