酒精所致震颤谵妄相关因素研究

Study on related factors of delirium tremens caused by alcohol

目的:研究使用酒精所致的精神和行为障碍患者出现震颤谵妄(delirium tremens,DT)的相关因素。方法:对118例首次住院的男性使用酒精所致精神和行为障碍患者,按照是否出现DT分为两组,对酒依赖年限、饮酒量和实验室检查(肝功、肾功、心肌酶、血细胞和电解质等)相关指标进行比较。结果:出现DT的51例患者,日饮酒量大,谷草转氨酶、谷氨酸转氨酶及肌酸激酶显著升高;而血红蛋白、红细胞、血小板及钾则显著降低,与非DT组相比,差异均有统计学意义(P<0.05或P<0.01)。结论:使用酒精所致的精神和行为障碍患者,日饮酒量大小,血液相关指标(转氨酶、心肌酶、血细胞及钾等)对DT具有一定意义。

Objective:To research related factors of delirium tremens for patients with mental and behavioral disorders caused by alcohol. Methods:118 male inpatients with mental and behavioral disorders caused by alcohol were divided into two groups ( deliri-um tremens and non delirium tremens) in terms of delirium tremens occurrence. The alcohol dependence years, alcohol consumption and laboratory examination ( hepatic function, renal function, myocardial enzyme, blood cells, and the electrolyte, etc. ) were com-pared. Results:Compared with non delirium tremens group, delirium tremens group (51 cases) showed higher daily alcohol consump-tion, AST, GGT, and CK, but lower Levels in HGB, HRB, PLT, and K, and the differences were statistically significant (P<0. 05 or P<0. 01). Conclusions:The blood related indexes and daily alcohol consumption of the inpatient with mental and behavioral disorders caused by alcohol to some degree can predict delirium tremens.