甲硝唑有效冲洗阑尾切口预防感染的研究

Study on prevention of appendix incision infection by effectively flushing with metronidazole

目的:探讨甲硝唑液的有效冲洗在预防阑尾切口感染时的临床疗效。方法:收集607例阑尾切除患者的临床资料予以回顾性分析。结果:单纯性阑尾炎208例,化脓性阑尾炎399例,穿孔合并腹膜炎者58例,阑尾周围脓肿23例;切口感染8例,感染率为1.3%。行脓液细菌培养,其中1例脓液有恶臭,细菌培养阴性,其余细菌培养均为大肠杆菌感染。结论:有效的甲硝唑冲洗切口,及早清除了感染源,有利于抗菌素发挥作用,局部抗炎明显预防了切口感染的机会。

ObjectiveTo study clinical effects of prevention of appendix incision infection by effectively flushing with metron-idazole. Methods：The clinical data of 607 cases of appendectomy were retrospectively analyzed. Results： There were 208 cases withsimple appendicitis, 399 cases with suppurative appendicitis, 58 cases with perforation combined with peritonitis, 23 cases with appen-diceal abscess, and 8 cases with incision infections with an infection rate of 1. 3%. A bacterial culture with pus was performed, where-in there was stench in one pus with a negative result of bacterial culture; however, the others were Escherichia coli infections. Conclu-sions： The method that metronidazole is used to effectively flush the incisions can early remove the source of infection, which is benefi-cial to the antibiotics and prevent the incision infections owing to the local anti-inflammation.