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左炔诺孕酮宫内缓释系统治疗子宫腺肌病疗效分析 被引量：1

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摘要 目的研究左炔诺孕酮宫内缓释系统(LNG-IUS,曼月乐)治疗子宫腺肌病(AM)患者月经异常和痛经的疗效。方法对60例AM患者放置LNG-IUS前后月经量、痛经、子宫体积、血红蛋白和激素水平[卵泡刺激素(FSH)、黄体生成素(LH)、雌二醇(E2)]的变化进行观察。结果放置LNG-IUS 3、6、12个月后患者月经量逐月减少;舒缓痛经,子宫体积缩小及贫血患者血红蛋白上升(P<0.01)。血清FSH、LH、E2水平无变化(P>0.05)。结论LNG-IUS治疗AM疗效显著,对卵巢功能无明显影响,值得临床应用推广。
作者 王莉
机构地区 河北省石家庄市中医院妇科
出处 《河北医药》 CAS 2014年第15期2305-2306,共2页 Hebei Medical Journal
关键词 子宫腺肌病 左炔诺孕酮宫内缓释系统 月经
分类号 R711.74 [医药卫生—妇产科学]
  • 相关文献

参考文献10

  • 1Sunkara SK, Khan KS. J Adenomyosis and female fertility: a critical re- view of the evidence. J Obstet Gynaeco1,2012,32 : 113-116.
  • 2Pepas L, Deguara C, Davis C. Update on the surgical management of ade- nomyosis. Curt Opin Obstet Gynecol,2012,24 : 259 -264.
  • 3Simon JA. Future developments in the medical treatment of abnormal u- terine bleeding: what can we expect ? Menopause,2011,18:462 -466.
  • 4Sheng J,Zhang WY, Zhang JP, et al. The LNG-IUS study on adenomyo- sis : a 3-year follow-up study on the efficacy and side effects of the use of levonorgestrel intrauterine system for the treatment of dysmenorrhea asso- ciated with adenomyosis. Contraception,2009,79:189-193.
  • 5邓姗,郎景和,冷金花,刘珠凤,孙大为,朱兰.左炔诺孕酮宫内缓释系统用于防治子宫内膜异位症和子宫腺肌病的临床观察[J].中华妇产科杂志,2006,41(10):664-668. 被引量：71
  • 6Janssen CA, Seholten PC, Heintz AP. A simple visual assessment tech- nique to discriminate between menerrhagia and normal menstrual blood loss. Obstet Gynecol,1995 ,85 :977-982.
  • 7Beatty MN, Blumenthal PD. The levonorgestrel-releasing intrauterine sys- tem: Safety, efficacy, and patient acceptability. Ther Clin Risk Manag, 2009,5:561-574.
  • 8Bragheto AM, Caserta N, Bahamondes L, et al. Effectiveness of the levonorgestrel-releasing intrauterine system in the treatment of adenomyo- sis diagnosed and monitored by magnetic resonance imaging. Contracep- tion ,2007,76 : 195-199.
  • 9Benagiano G,Brosens l,Carrara S, Adenomyosis: new knowledge is gen- erating new treatment strategies. Womens Health (Lond Engl) ,2009,5: 297-311.
  • 10He SM, Zhang YD. Clinical study of levonorgestrel-releasing intrauterine system for adenomyosis. Nan Fang Yi Ke Da Xue Xue Bao, 2006,26: 1794-1796.

二级参考文献11

  • 1Critchley H.Endometrial effects of progestogens.Gynecol Forum,2003,8:6-10.
  • 2Vercellini P,Aimi G,Panazza S,et al.A levonorgestrel-releasing intrauterine system for the treatment of dysmenorrheal associated with endometriosis:a pilot study.Fertil Steril,1999,72:505-508.
  • 3ACOG Committee on Practice Bulletins-Gynecology.ACOG practice bulletin.Medical management of endometriosis.Number 11,December 1999 (replaces Technical Bulletin Number 184,September 1993).Clinical management guidelines for obstetrician-gynecologists.Int J Gynaecol Obstet,2000,71:183-196.
  • 4Olive DL.Medical therapy of endometriosis.Semin Reprod Med,2003,21:209-222.
  • 5Luukkainen T,Lahteenmaki P,Toivonen J.Levonorgestrel-releasing intrauterine device.Ann Med,1990,22:85-90.
  • 6Spaczynski RZ,Duleba AJ.Diagnosis of endometriosis.Semin Reprod Med,2003,21:193-208.
  • 7Xiao B,Zeng T,Wu S,et al.Effect of levonorgestrel-releasing intrauterine device on hormonal profile and menstrual pattern after long-term use.Contraception,1995,51:359-365.
  • 8Luukkainen T,Lahteenmaki P.Treatment of menorrhagia by levonorgestrel-releasing intrauterine device.Immunology,1992,36:261-267.
  • 9McGavigan CJ,Dockery P,Metaxa-Mariatou V,et al.Hormonally mediated disturbance of angiogenesis in the human endometrium after exposure to intrauterine levonorgestrel.Hum Repord,2003,18:77-84.
  • 10郎景和.子宫内膜异位症基础与临床研究的几个问题[J].中国实用妇科与产科杂志,2002,18(3):129-130. 被引量：301

共引文献70

同被引文献24

  • 1徐永中.米非司酮治疗子宫内膜异位症疗效及对子宫内膜PCNA的影响[J].医学临床研究,2005,22(6):789-790. 被引量：1
  • 2郭方,徐丛剑.子宫内膜异位症药物治疗研究进展[J].中国妇幼健康研究,2006,17(6):510-513. 被引量：6
  • 3谢幸,苟文丽.妇产科[M].8版.北京:人民卫生出版社,2013:126.
  • 4Allen C, Hopewell S, Prentice A, et al. Non-steroidl anti-intlam- matory drugs for pain in women with endometriosis[ J3. Cochrane Database Syst Rev,2005, (4) :CD004753.
  • 5Tokushige N, Markham R, Russell P, et al. Effect of progestogens and combined oral contraceptives on nerve fibers in peritoneal en- dometfiosis [ J ]. Fertil Steri1,2009,92 (4) : 1234-1239.
  • 6Abou-Setta AM, Al-Inany HG, Farquhar CM. Levonorgestrel-re- leasing intrautering device (LNG-IUD) for symptomatic endometri- osis following surgery [ J ]. Cochrane Database Syst Rev, 2006, (4) : CD005072.
  • 7WSlfler MM, Nagele F, Kotbus A, et al. A predictive model for en- dometriosis [ J ]. Hum Reprod, 2005,20 ( 6 ) : 1702 -1708.
  • 8Shippen ER,West WJ Jr. Successful treatment of severe en dom- etriosis in two premenopausal women with an aromatase inhibitor [ J]. Fertil Steril,2004,81 (5) : 1395-1398.
  • 9Lu D, Song H, Shi G. Anti-TNF-a treatment for pelvic pain associ- ated with endometriosis [ J ]. Cochrane Database Syst Rev,2013, (3) N: CD008088.
  • 10陆建萍,宋丽杰,徐英娣.子宫内膜异位症术后口服避孕药治疗[J].中国临床医学,2009,16(5):761-763. 被引量：7

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河北医药
2014年 第15期

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