低温等离子消融用于小儿腺样体手术的效果与机制

The Mechanism and the Effects of DNR Applied to the Children Undergoing the Operation of Adenoids

目的:探讨低温等离子消融用于小儿腺样体手术的效果与机制。方法:将腺样体肥大小儿120例根据治疗方法的不同分为治疗组与对照组各60例,对照组予鼻内镜下手术治疗,治疗组在此基础上予低温等离子消融辅助治疗。结果:治疗组与对照组的显效率分别为91.7%和80.0%,组间比较差异有统计学意义(P<0.05)。治疗组小儿术中出血量与手术时间明显少于对照组(P<0.05)。治疗前2组小儿LSa02与AHI值比较无明显差异,治疗后AHI值明显降低,LSa02值明显升高(P<0.05),2组比较差异明显(P<0.05)。随访3个月,治疗组小儿日常活动、社会互动、情感与症状得分明显高于对照组(P<0.05)。结论:低温等离子消融辅助治疗小儿腺样体肥大能提高疗效,减少创伤,提高术后生存质量,其疗效机制的发挥可能与改善呼吸参数有关。

Objective： To explore the mechanism and the effects of DNR in treating children undergoing the operation of adenoids. Methods： All 120 cases were divided in to two groups. The control group received the surgery under nasal endoscopy, and the treatment group DNR on the foundation of the operation. Results： Excellence rates of the treatment group and the control group were respectively 91.7% and 80.0%, the difference had statistical mean-ing （P〈0.05）. The treatment group was obviously less than the control group in bleeding amount and surgical time （P〈0.05）. The comparison between both groups before treating demonstrated no significant difference in LSa02 and AHI value, after treating, AHI was decreased and LSa02 raised remarkably （P〈0.05）, the difference between both groups after treating was notable （P〈0.05）. In three months after the patients were followed up, the treatment group was higher than the control group in the scores of daily activities, social interaction, emotion and symptoms evidently （P〈0.05）. Conclusion： DNR as adjunctive therapy in treating the children with adenoid hypertrophy could improve clinical effects, reduce the trauma, improve life quality after the surgery, and the mechanism might be related to im-proving respiratory parameters.