摘要
目的：研究广东顺德1954～2103年用氨苯砜单疗或联合化疗后麻风病患者的复发情况。方法对1954～2013年顺德开展麻风病防治工作较完整的麻风个案资料进行分析。结果1954～2013年间顺德累计复发患者64例，累计复发率为4.77％。平均治愈-复发间隔为（131.52±12.64）个月。多菌型的累计复发率高于少菌型的累计复发率（χ2＝76.771， p＜0.0001）。男女的复发率无统计学意义（χ2＝2.349，p＝0.125）。利福平600 mg＋氧氟沙星400 mg联合化疗治愈患者的复发率为27.27％，高于其他联合化疗方案和氨苯砜单疗的复发率（χ2＝7.974，p＝0.034）。结论采用利福平和氧氟沙星联合化疗方案治愈的患者，其复发率远高于其他化疗方案，不建议继续使用和推广。麻风复发有长期危险性，长期监测随访，有助于发现复发患者。
Objective To study on leprosy relapse cases after DDS or MDT in Shunde City from 1954 to 1998. Methods The data of leprosy relapse cases in Shunde City from 1954 to 1998 were analyzed.Results There were a total of 64 leprosy relapse cases during 1954~1998 in Shunde City, and the relapse rate was 4.77%.The average of cure and Re-currence time were （131.52 ±12.64） months.The relapse rate of MB cases were higher than PB cases （χ2 =76.771, p〈0.000 1）.The relapse rate for male and female were not statistical significance （χ2 =2.349, p=0.125）.The relapse rate of Chemotherapy with RFP （600 mg） and OFLO （400 mg） was 27.27%.It was higher than other treatment plans （χ2=7.974,p=0.034）.Conclusion The relapse rate of Chemotherapy with RFP and OFLO were higher than other kinds of treat-ment plans, and it not recommended again.Long-term follow-up can help us to find relapse cases.
出处
《现代医院》
2014年第8期19-20,共2页
Modern Hospitals
