参芍葡萄籽提取物方剂对小鼠免疫调节作用的实验研究

Study of Shenshao & Grape Seed Extract for Immunomodulatory Effects in Mice

目的探讨参芍葡萄籽提取物方剂对环磷酰胺致免疫抑制小鼠免疫功能的调节作用。方法对免疫抑制小鼠进行免疫器官重量影响、迟发型超敏反应、血清溶血素实验、小鼠碳廓清实验,统计各个指标结果。结果参芍葡萄籽提取物方剂对免疫抑制小鼠的免疫调节作用显著,免疫器官重量、迟发型超敏反应、血清溶血素实验和小鼠碳廓清实验结果均为阳性。结论参芍葡萄籽提取物方剂具有较好的免疫调节作用。

Objective To investigate the effect of Shenshao＆grape seed extract on cyclophosphamide-induced immunosuppressed mice. Methods Immunosuppressed mice were used for experiment on the effect of experimental immune organ weight, delayed type hypersensitivity test, serum hemolysin experiment, mice carbon clearance test, and the results of the various indicators were taken for statistical analysis. Results Shenshao＆grape seed extract had significant immunomodulatory effects for immunosuppressed mice, and the results of immune organ weight, delayed type hypersensitivity, serum hemolysin experiments, and mice carbon clearance test were positive. Conclusions Shenshao＆grape seed extract has a good immune regulation.