董氏奇穴治疗非糜烂性反流病的临床疗效及患者生存质量观察

Observation of the Efficacy of Dong's Extraordinary Acupoints in the Treatment of Non-Erosive Reflux Disease and Effect on Patients' Quality of Life

目的探索董氏奇穴治疗非糜烂性反流病(NERD)对患者的临床疗效及生存质量的改善情况。方法按纳入排除标准筛选NERD患者80例,随机分为治疗组和对照组各40例,分别接受董氏奇穴配合PPI治疗和单纯PPI治疗8周后,比较两组患者临床疗效、反流性疾病问卷(RDQ)评分及世界卫生组织生存质量测定量表简表(WHOQOL-BREF)评分变化情况。结果治疗组临床疗效显著优于对照组(P<0.05);治疗组患者RDQ总分、WHOQOL-BREF评分较对照组均有显著改善(P<0.05)。结论董氏奇穴疗法能够显著提高口服PPI治疗的NERD患者临床疗效,提高患者生存质量。

Objective To explore the improvement of the clinical efficacy of Dong＇s extraordinary acupoints in the treatment of non-erosive reflux disease （NERD） and patients＇ quality of life （QOL）. Methods 80 patients with NERD were selected and randomly divided into two groups, with 40 cases in each group. Patients in the treatment group were treated with Dong＇s extraordinary acupoints combined with proton pump inhibitors （PPI） for 8 weeks, while patients in the control group were treated with PPI for 8 weeks only. The clinical efficacy, score of reflux diagnostic questionnaire （RDQ） and score of WHO quality of life-BREF （WHOQOL-BREF） were observed and compared between two groups. Results The clinical effect of treatment group was significantly better than that of control group （P〈0.05）. The total RDQ score and WHOQOL-BREF score of treatment group were significantly better than those of control group （P 〈0.05）. Conclusions Dong＇s extraordinary acupoints therapy can improve the clinical efficacy on NERD treated with PPIs, reduce the frequency of the symptom, and improve patients＇ quality of life.