急性脑卒中偏瘫患者的抑郁发病率及相关因素分析

Study on the Incidence of Depression and Related Factors of Acute Stroke Patients with Hemiplegia

目的观察急性脑卒中偏瘫患者抑郁的发生,分析影响急性脑卒中偏瘫患者发生抑郁的因素。方法选取2009-12—2012-12在我院住院治疗的急性脑卒中偏瘫患者194例为研究对象。统计194例患者抑郁的发生率,对抑郁和非抑郁患者进行神经功能缺损和日常生活能力评估,分析急性脑卒中偏瘫患者发生抑郁的影响因素。结果 SDS评分≥50分78例,SAS评分≥50分81例。单纯焦虑18例,单纯抑郁15例,焦虑伴抑郁63例。抑郁患者的日常生活能力评分和神经功能缺损评分与非抑郁患者相比差异具有统计学意义(P<0.05)。根据抑郁发生率影响因素的单因素分析显示,病变部位、病程以及NDS可能与抑郁发生有关。Logistic回归分析显示,病变部位、病程及NDS与抑郁发生具有相关性。结论病变部位、病程及NDS会影响急性脑卒中偏瘫患者发生抑郁,应该采取恰当的预防措施降低抑郁的发生率。

Objective To observe and analyze the Incidence of Depression and Related Factors of Patients with Hemiplegia caused by Acute Stroke.Methods 194 patients with hemiplegia admitted to our hospital from December 2009 to December 2012 were selected as the object of study. The incidence of depression in the 194 cases of patients was analyzed ,evaluation of neural function defect and activities of daily living in patients with depression and non-depression were conducted ,and the influencing factors of depression were analyzed.Results Patients with SDS score ≥ 50 points took up 78 cases ,those with SAS score ≥50 points were 81 cases. Patients with mere anxiety were 18 cases ,and 15 cases with depression ,63 cases with anxiety and de-pression. Scores of activities of daily living and neurologic impairment scores of patients with depression were significantly dif-ferent from those of non depressive patients ,and the difference was statistically significant （P〈0.05）. The single factor analy-sis showed that location of the lesion ,duration of the disease and NDS might be associated with depression. Logistic regression analysis showed the lesion site ,duration and NDS were indeed associated with depression.Conclusion The lesion site ,duration and NDS are influencing factors of patients with hemiplegia caused by acute stroke who suffer from depression ,and appropriate preventive measures for such patients should be taken to reduce the incidence of depression.