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以“呃逆”为首发症状的视神经脊髓炎临床报道1例 被引量：4

Neuromyelitis Optia with Hiccup as the Primary Symptom: 1 Case Report
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摘要 目的报道临床中以呃逆为首发症状的视神经脊髓炎。方法根据临床的症状、体征,对1例视神经脊髓炎患者进行相关实验室检查,特别是水通道蛋白4。结果水通道蛋白4在该患者中呈抗体阳性。结论水通道蛋白4可能在视神经脊髓炎发病过程中起重要作用。 Objective To report a case of neuromyelitis optia with hiccups as the first symptom. Methods 1 case received laboratory examination according to the clinical symptoms, signs, especially aquaporin-4. Results Aquaporin-4 antibody was positive. Conclusion Aquaporin-4 may play an important role in the pathogenesis of neuromyelitis optia.
作者 田伟
机构地区 首都医科大学康复医学院 中国康复研究中心北京博爱医院
出处 《中国康复理论与实践》 CSCD 北大核心 2014年第7期681-682,共2页 Chinese Journal of Rehabilitation Theory and Practice
关键词 呃逆 视神经脊髓炎 水通道蛋白4 hiccup neuromyelitis optia aquaporin-4
分类号 R744.52 [医药卫生—神经病学与精神病学]
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参考文献5

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  • 1Papeix C, Vidal JS, de seze J, et al. Immunosuppressive therapy is more effective than interferon in neuromyelitis optica [J]. Mult Scler, 2007, 13(2): 256-259.
  • 2Wingerchuk DM, Lennon VA, Pittock S J, et al. Rivised diagnostic criteria for neuromyelitis optica [J]. Neurology, 2006, 66 (10): 1485-1489.
  • 3Lennon VA, Kryer T J, Pittock S J, et al. IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water chamlel[J]. J Exp Med, 2005, 202(4): 473-477.
  • 4Lennon VA, Wingerchuck DM, Kryer T J, et al. A serum autoantibody mark of neuromyelitis optiea: distinction from multiple sclerosis[J]. Lancet, 2004, 364(9451): 2106-2112.
  • 5Misu T, Fujihara K, Nakashima I, et al. Intractable hiccup and nausea with periaqueductal lesions in neuromyelitis optica [J]. Neurology, 2005, 65(9): 1479-1482.
  • 6Milano E, Disapi A, Malucchi S, et al. Neuromyelitis optica: importance of cerebrospinal fluid examination during relapse [J]. Neurol Sci, 2003, 24(3): 130-133.
  • 7Bergamaschi R, Tonietti S, Franciotta D, et al.Oligclonal bands in Devic's neuromyelitis optica and multiple sclerosis:differences in repeated cerebrospinal fluid examinations[J]. Mult Scler, 2004, 10 (I): 2-4.
  • 8de Seze J, Lebrun C, Stojkovic T, et al. Is devic's neuromyelitis optica a separate disease? A comparative study with multiple sclerosis[J]. Mult Scler, 2003, 9(5): 521-522.
  • 9Misu T, Fujihara K, Nakaslaima I, et al. Pure opticspinal form of multiple sclerosis in Japan[J]. Brain, 2002, 125(Pt 11): 2460-2468.
  • 10Misu T, Fujihara K, Kakita A, et al. Loss of aquaporin-4 in lesions of neuromyelitis optica: distinction from multiple sclerosis [J]. Brain, 2007, 130(Pt 5): 1224-1234.

共引文献141

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中国康复理论与实践
2014年 第7期

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