摘要
糖尿病肾病(DN)是引起终末期肾病的常见原因之一,目前蛋白尿的变化被认为是DN发生或进展的一个非侵入性的检测生物标记。一些糖尿病患者即使尿微量白蛋白水平在正常范围内,但已有肾脏病理改变和肾功能衰退。蛋白尿在DN的早期诊断是不完全准确的。该文就与DN相关的生物标志物,特别是肾损伤、炎症和氧化应激时的生物标志物予以综述。
Diabetic nephropathy（DN） is a common cause of end-stage renal disease,the change level of proteinuria is now regarded as a non-invasive detecting biomarkers of the occurrence or progression of DN.However,some diabetes patients even have the urine albumin levels within the normal range,they still have pathological changes and function decline in kidney.Therefore,only relying on the level of proteinuria in the early diagnosis of DN is inaccurate,Here is to make a review of the biomarkers associated with DN,especially those kidney injury,inflammation and oxidative stress.
出处
《医学综述》
2014年第14期2604-2606,共3页
Medical Recapitulate
